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Author(s): Sanjiv M Narayan , David E Krummen Added: 3 years ago
Atrial fibrillation (AF) is the most prevalent arrhythmia in the world and a leading cause of hospitalisation and death.1 Current therapy for AF remains suboptimal, in large part because its mechanisms are uncertain. However, recent advances in our understanding of human AF, from meticulous mapping in patients and insights from animal models, are providing new therapeutic options for patients. … View more

Electrophysiology & Arrhythmia
Biophysics of Cryoballoon Ablation in Atrial Fibrillation
Author(s): Jason G Andrade , Roland R Tilz , Richard Schilling Start date: Oct 25, 2018

Electrophysiology & Arrhythmia
The Cutting Edge of Atrial Fibrillation Ablation
Author(s): Maya S Verma , Maria Terricabras , Atul Verma Added: 2 years ago

Electrophysiology & Arrhythmia
Anticoagulation in Atrial Fibrillation – Current Concepts
Author(s): Demosthenes G Katritsis , Bernard J Gersh , A John Camm Added: 3 years ago
Thrombotic material in atrial fibrillation(AF) usually develops in the left atrial appendage as a result of decreased flow and stasis, possible endothelial dysfunction and a hypercoagulable state as indicated by increased fibrinogen, D-dimer, thromboglobulin and platelet factor 4 levels.1 In the Framingham Heart Study, the percentage of strokes attributable to AF increases steeply from 1.5 % in… View more

Anticoagulation

Standards & Guidelines
Author(s): Jean-Baptiste Gourraud , Jason G Andrade , Laurent Macle , et al Added: 3 years ago
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia observed in clinical practice, occurring in approximately 2 % of the general population.1–3 A progressive increase in both the prevalence and incidence of AF has been demonstrated in recent years, defining AF as a major economic and public health issue.1 The identification of sites of AF initiation and/or maintenance within… View more

Electrophysiology & Arrhythmia

Prevention & Chronic Conditions
Author(s): Ling Zhang , Yuemei Hou , Sunny S Po Added: 3 years ago
Atrial fibrillation(AF) is the most frequently encountered arrhythmia in clinical practice and has become an emerging epidemic. AF is associated with increased cardiovascular mortality and morbidy such as stroke.1–3 Over 2.3 million people in the US are affected by AF: it is estimated that AF will affect more than 15 million Americans by 2050.3 The traditional risk factors implicated in the… View more

Electrophysiology & Arrhythmia

Prevention & Chronic Conditions
Cardiac MRI to Manage Atrial Fibrillation
Author(s): Yan Zhao , Lilas Dagher , Chao Huang , et al Added: 3 years ago
AF is a common arrhythmia in clinical practice, with a prevalence of 2.7–6.1 million that is expected to rise to 5.6–12 million by 2050 in the US alone.1,2 Patients with AF have an increased risk of stroke and mortality and a decreased quality of life.3 In addition, management of AF increases the cost of healthcare.4,5,6 The mechanisms of AF are complex and are associated with electric and… View more

Imaging & Diagnostics
Author(s): Marco Alings Added: 3 years ago
Atrial Fibrillation(AF) is the most common cardiac arrhythmia, with the highest prevalence in elderly patients, and is characterised by an irregular heart rhythm that may result in clots in the heart that can spread throughout the circulatory system. It is seen in approximately 2 % of the European adult population and is a significant cause of increasing healthcare costs in developed countries.1… View more

Anticoagulation

Electrophysiology & Arrhythmia
Author(s): C Fielder Camm , A John Camm Added: 3 years ago
Hypertrophic cardiomyopathy (HCM) is a common genetic cardiac disorder, with an autosomal dominant mechanism of inheritance.1,2 It has a prevalence of 1 in 500 within the general population, and is a known cause of sudden cardiac death.2,3 Recognised autosomal dominant mutations within sarcomere proteins are found in 55 % of adolescents with sporadic HCM.4 Characteristic echocardiographic… View more

Heart Failure
Reconceptualising Atrial Fibrillation Using Renewal Theory: A Novel Approach to the Assessment of Atrial Fibrillation Dynamics
Author(s): Jing Xian Quah , Dhani Dharmaprani , Anandaroop Lahiri , et al Added: 2 years ago

Electrophysiology & Arrhythmia