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3 years ago
In patients with syncope or episodes of palpitations and heart disease, an electrophysiology study (EPS) may be of value by means of potential induction of sustained ventricular tachyarrhythmias.1,2 Programmed ventricular stimulation may be useful in the context of risk stratification of ischaemic patients with left ventricular ejection fraction (LVEF) 30–40 %, and there has been some evidence…
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3 years ago
The number of invasive electrophysiological procedures is steadily increasing in Western countries, as techniques advance and the age of the population increases. Gender exerts a profound influence on the epidemiology, pathophysiology and clinical presentation of many cardiac rhythm disorders, and all these factors may affect the outcome of invasive electrophysiological procedures. Disturbingly,…
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3 years ago
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia observed in clinical practice, occurring in approximately 2 % of the general population.1–3 A progressive increase in both the prevalence and incidence of AF has been demonstrated in recent years, defining AF as a major economic and public health issue.1
The identification of sites of AF initiation and/or maintenance within…
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3 years ago
Sudden cardiac death (SCD) is a major public health concern worldwide, accounting for 50 % of cardiovascular mortality.1 Reduced left ventricular ejection fraction (LVEF) is presently used to identify patients at high risk for primary prevention using implantable cardioverter defibrillator (ICD) therapy, but currently only a minority of patients meeting the criteria for prophylactic ICD receive…
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3 years ago
Since its initial description by Jervell and Lange-Nielsen in 1957,1 congenital long QT syndrome (LQTS) has been the most investigated cardiac ion channelopathy. A prolonged QT interval on the surface ECG is a surrogate measure of prolonged ventricular action potential duration (APD).
Congenital as well as acquired alterations in certain cardiac ion channels can affect their currents in such a…
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3 years ago
Historical Precedents
Brugada syndrome (BrS) was first described more than 25 years ago as a clinical entity in people resuscitated from sudden cardiac death due to documented VF.1 The original 1992 case series described eight patients without apparent structural heart disease who all had VF associated with persistent coved ST-segment elevation in the right precordial leads.1 In 1996 this…
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3 years ago
Interventional magnetic resonance imaging (MRI) is a growing field, and the strength of MRI guidance for procedures rests fundamentally in the high-contrast imaging of soft tissue structures. Combined with the avoidance of radiation exposure, the potential for functional assessment and the ability to exploit MR signals for calculation of the location of interventional instruments, it is clear…
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Cardiac Device Allergies
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1 year ago
Article
Added:
3 years ago
Brugada syndrome (BrS) is a clinical entity identified in 1992 by Brugada brothers from a file of patients resuscitated from sudden cardiac death (SCD).1 Of these patients, some had a specific electrocardiogram (ECG) appearance characterised by an incomplete right bundle branch block associated with an ST segment elevation in the right precordial leads. It quickly became apparent that this…
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1 year ago
