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Author(s): Tom Nelson , Pankaj Garg , Richard H Clayton , et al Added: 3 years ago
Ventricular tachycardia (VT) and VF occur mainly in people with impaired cardiac function and/or ischaemic heart disease, and account for the majority of sudden cardiac deaths worldwide.1 Treatment with anti-arrhythmic drugs such as amiodarone may be at best neutral in terms of mortality and carries significant long-term risks.2,3 While ICDs significantly improve survival for patients with… View more
Author(s): Angelo Auricchio Added: 3 years ago
Despite the fact that more than 20 years have passed since the clinical introduction of cardiac resynchronisation therapy (CRT), one of the key questions – do we need an ICD for primary prevention of sudden cardiac death (SCD) in CRT patients? – is still unanswered. Prospective Randomised Controlled Trials Multiple prospective randomised controlled trials have been conducted to establish the… View more
Job title: Clinical Director of Imaging
Personal History Prof James C. Moon is a Cardiology Professor at University College London and Clinical Director of Imaging at Barts Heart Centre. He is known for the use of cardiac MRI and for developing mapping techniques to bridge clinical and basic investigators.5 Academic History Professor Moon graduated with a BA from the University of Cambridge in 1992. He then went on to… View more
Author(s): Yan Zhao , Lilas Dagher , Chao Huang , et al Added: 3 years ago
AF is a common arrhythmia in clinical practice, with a prevalence of 2.7–6.1 million that is expected to rise to 5.6–12 million by 2050 in the US alone.1,2 Patients with AF have an increased risk of stroke and mortality and a decreased quality of life.3 In addition, management of AF increases the cost of healthcare.4,5,6 The mechanisms of AF are complex and are associated with electric and… View more
Author(s): Stylianos Tzeis , Dimitrios Asvestas , Panos Vardas Added: 3 years ago
AF is the most common cardiac arrhythmia with a complex and multifactorial pathophysiological background. In their seminal publication, Haissaguerre et al. shed light on the role of rapidly firing pulmonary vein sources in the initiation of AF paroxysms.1 Apart from the role of pulmonary vein-triggering foci, underlying electrical and structural remodelling also contributes to the onset and… View more
Author(s): Demosthenes G Katritsis Added: 3 years ago
Cardiology has traditionally been a high-tech subspecialty, and in no field is this more true than interventional cardiac electrophysiology. Following the advent of computer-assisted recording systems and electroanatomic mapping, impressive technological innovations are emerging. Fusion of intracardiac ultrasound, or cardiac CT, and cardiovascular magnetic resonance (CMR)-derived imaging to… View more
Author(s): Ethan J Rowin , Martin S Maron Added: 3 years ago
Hypertrophic cardiomyopathy (HCM), the most common genetic cardiomyopathy, is present in one in 500 of the general population and is caused by over 1,400 mutations in at least 11 genes encoding the cardiac sarcomere.1–4 Although the majority of patients with HCM remain asymptomatic with near-normal longevity, a small, but important, subset of patients are at increased risk for a wide range of… View more
Author(s): Ling Kuo , Jackson J Liang , Saman Nazarian , et al Added: 3 years ago
Catheter ablation has been increasingly used as a treatment for refractory ventricular tachycardia (VT) in patients with non-ischaemic cardiomyopathy (NICM). However, ablation outcomes tend to be quite variable because of the heterogeneity of the aetiology for the NICM and associated VT substrate in these patients.1–3 Patients with NICM can be sub-classified based on specific genotypic and… View more
Author(s): Brenton S Bauer , Anthony C Li , Jason S Bradfield Added: 3 years ago
Ventricular arrhythmias (VA) are commonly associated with structural heart disease and have substantial impact on patient outcomes and health system costs. Within the realm of cardiomyopathy (CM), there has been substantial progress with respect to ischaemic CM (ICM) in the understanding of infarct related scar biology and scar-mediated ventricular tachycardia (VT). This has led to interventions… View more