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Author(s): Josef Kautzner , Petr Peichl Added: 3 years ago
Ventricular fibrillation (VF) is a complex arrhythmia that leads invariably to cardiac arrest. Its mechanisms remain largely unclear. Similar to atrial fibrillation, the mother rotor hypothesis is one plausible alternative.1,2 In larger animals, some authors reported that the dominant frequency of VF could be recorded at a junction of the left ventricular posterior wall and the septum.3-6 Others… View more

Electrophysiology & Arrhythmia

MI/ACS
Author(s): Jan M Griffin , Jason N Katz Added: 3 years ago
Prior to the widespread availability of left ventricular assist devices (LVADs), many end-stage heart failure patients were forced to fight over scarce transplant resources or face the reality of impending death. For those considered transplant-ineligible, due to medical or psychosocial factors, symptom palliation and end-of-life care were the only available options. This all changed dramatically… View more

Electrophysiology & Arrhythmia
Catecholaminergic Polymorphic Ventricular Tachycardia
Author(s): Mohamed Abbas , Chris Miles , Elijah R Behr Added: 1 year ago

Electrophysiology & Arrhythmia

CV Disease in Special Populations
Author(s): David J Callans Added: 3 years ago
Premature ventricular contractions (PVCs) are very common cardiac arrhythmias, detected on up to 75% of Holter monitors of ambulatory patients.1 Although PVCs in the setting of advanced structural heart disease have independent negative prognostic implications,2 the majority of PVCs are quite benign, associated with neither symptoms nor signals of future harm. For an important minority, PVCs… View more

Heart Failure
Author(s): Simon Ermakov , Melvin Scheinman Added: 3 years ago
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited cardiomyopathy characterised by progressive replacement of the ventricular myocardium by fibrofatty tissue.1 Patients with the disease are predisposed to ventricular arrhythmias, heart failure and sudden cardiac death. Pathophysiology ARVC has a strong genetic basis with most disease variants displaying an autosomal dominant… View more

Standards & Guidelines

Heart Failure
Author(s): Jeffrey J Hsu , Ali Nsair , Jamil A Aboulhosn , et al Added: 3 years ago
Monomorphic ventricular arrhythmias (MMVA) are not uncommon in athletes,1,2 yet their presence appropriately raises concern among practitioners for possible increased risk of sudden cardiac death (SCD) during sports activity and competition. While all MMVA detected in athletes warrant further evaluation,1 a majority of MMVA in this population are likely to be benign. In some instances of so… View more

Heart Failure

Electrophysiology & Arrhythmia
Author(s): Sebastiaan RD Piers , Katja Zeppenfeld Added: 3 years ago
Over the last 20 years ventricular tachycardia (VT) ablation has evolved from a treatment modality for selected patients withrecurrent haemodynamically tolerated VT (which can be mapped during ongoing arrhythmia), to a therapeutic option for patients with tolerated and untolerated VT using substrate-based ablation strategies.1 The substrate for VT after myocardial infarction (MI) consists of… View more

Imaging & Diagnostics

Electrophysiology & Arrhythmia
Author(s): Eyal Nof , William G Stevenson , Roy John Added: 3 years ago
Sustained ventricular tachycardia (VT) and ventricular fibrillation (VF) are typically a manifestation of significant structural heart disease and often associated with a high risk of sudden cardiac death. Implantable cardioverter defibrillators (ICDs) remain the mainstay of therapy for prevention of sudden cardiac death associated with these arrhythmias.1 However, ICDs treat the arrhythmia after… View more

Electrophysiology & Arrhythmia
Author(s): Jorge G Panizo , Sergio Barra , Greg Mellor , et al Added: 3 years ago
Premature ventricular complexes (PVCs) are the most common ventricular arrhythmia. Their prognostic significance cannot be interpreted without considering the presence or absence of any associated underlying cardiac condition. In the absence of structural heart disease, PVCs were generally considered to be benign.1,2 In the 1970s and 1980s, it was postulated that frequent PVCs could be a trigger… View more

Heart Failure

Electrophysiology & Arrhythmia
Wide Complex Tachycardia - Ventricular Tachycardia or Not Ventricular Tachycardia, That Remains the Question
Author(s): John B Garner , John M Miller Added: 3 years ago
A wide complex tachycardia (WCT) is simple enough to define: a cardiac rhythm with a rate >100 beats per minute and a QRS width >120 milliseconds (ms). Unfortunately, beyond this simple definition lies a complex differential diagnosis with prognoses ranging from utterly benign to potentially lethal, requiring treatment strategies ranging from medications to emergent non-sedated… View more

Electrophysiology & Arrhythmia