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Author(s):
Ling Kuo
,
Jackson J Liang
,
Saman Nazarian
,
et al
Added:
3 years ago
Catheter ablation has been increasingly used as a treatment for refractory ventricular tachycardia (VT) in patients with non-ischaemic cardiomyopathy (NICM). However, ablation outcomes tend to be quite variable because of the heterogeneity of the aetiology for the NICM and associated VT substrate in these patients.1–3 Patients with NICM can be sub-classified based on specific genotypic and…
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Author(s):
Michael Ghannam
,
Hakan Oral
Added:
3 years ago
Maintenance of sinus rhythm in patients with non-paroxysmal AF is often challenging and complex. Catheter ablation is usually superior to anti-arrhythmic drug therapy alone. However, recurrence rates are high and have remained suboptimal. Although pulmonary vein isolation (PVI) is usually effective in treating paroxysmal AF, it is not sufficient for many patients with non-paroxysmal AF,…
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Author(s):
Steven M Markowitz
,
George Thomas
,
Christopher F Liu
,
et al
Added:
3 years ago
Pioneering electrophysiology studies in the 1990s defined the anatomical boundaries of typical atrial flutter, identified regions for effective catheter ablation of this arrhythmia and described procedural endpoints to minimise recurrences after ablation. Activation and entrainment mapping demonstrated that typical flutter arises from reentry around the tricuspid annulus.1 Criteria to confirm…
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Author(s):
Jackson J Liang
,
Pasquale Santangeli
,
David J Callans
Added:
3 years ago
Ventricular tachycardia (VT) is a significant cause of morbidity and mortality in patients with structural heart disease (SHD). While implantable cardioverter-defibrillators (ICDs) have been shown to be effective in preventing sudden death due to ventricular arrhythmias, they are not able to prevent recurrent VT episodes. Antiarrhythmic drugs (AADs) have some demonstrated efficacy in preventing…
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Author(s):
Domenico G Della Rocca
,
Sanghamitra Mohanty
,
Chintan Trivedi
,
et al
Added:
3 years ago
AF is the most common sustained arrhythmia, and carries an increased risk of cardiovascular and cerebrovascular complications. The latest estimates on the prevalence of AF portray an alarming scenario, with a steep increase in the number of people developing AF and prediction that the number affected will more than double in the next 40 years.1 Among the strategies to restore and maintain sinus…
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Author(s):
Tauseef Akhtar
,
Ronald Berger
,
Joseph E Marine
,
et al
Added:
3 years ago
AF is a common and clinically impactful arrhythmia. Given both the association of AF with aging and the increasing number of elderly people in the general population, it follows that many AF patients are of advanced age. The management of AF in the geriatric population is associated with several challenges, including multiple comorbidities, increased toxicity of antiarrhythmic drugs (AAD), an…
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Author(s):
Sanghamitra Mohanty
,
Andrea Natale
Added:
2 years ago
Author(s):
Yoga Waranugraha
,
Ardian Rizal
,
Mohammad Saifur Rohman
,
et al
Added:
1 year ago
Author(s):
Amit J Thosani
,
Paul Gerczuk
,
Emerson Liu
,
et al
Added:
3 years ago
Atrial fibrillation (AF) is the most common cardiac arrhythmia worldwide. In 2010, the prevalence of AF in the US was estimated at 5.9 million.1 The decision to pursue treatment to maintain sinus rhythm is driven by disabling symptoms related to AF; including palpitations, dyspnoea, fatigue, stroke and congestive heart failure. Percutaneous catheter-based ablation is an established therapy for…
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Author(s):
Satoshi Higa
,
Li-Wei Lo
,
Shih-Ann Chen
Added:
3 years ago
Catheter ablation of AF has become an established therapy and may have the potential to cure this most commonly encountered sustained arrhythmia. Previous studies have demonstrated that pulmonary veins (PVs) are a major source of the ectopic beats that initiate AF. PV isolation in patients with symptomatic paroxysmal AF refractory to antiarrhythmic drugs is effective; however, it is difficult to…
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