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Challenges Associated with Interpreting Mechanisms of AF

… mechanisms for AF, ranging from hierarchical drivers to anarchical multiple activation wavelets. Differences in the assessment of AF mechanisms are …

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Article

Drivers of Atrial Fibrillation: Theoretical Considerations and Practical Concerns

… was based on a meandering central or mother wave moving in multiple directions and giving rise to daughter waves. While … and producing independent, randomly wandering daughter wavelets as offspring (the multiple wavelet hypothesis). To further challenge this …

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Article

The Role of the Electrophysiologist in Convergent Ablation

… regarding the mechanism of the maintenance of AF: multiple independent wavelets, re-entrant rotors and the double-layer hypothesis. The multiple wavelet hypothesis was first described by Moe et al. …

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Article

Mechanisms of Atrial Fibrillation – Reentry, Rotors and Reality

… Historical Mechanisms of Atrial Fibrillation and the Multiple Wavelet Hypothesis Interest and understanding of the … technology of the time. In 1959, Moe et al. described the 'multiple wavelet hypothesis' of AF which extended the concept … perpetuate. However, if the number of simultaneous wavelets were small and/or below a critical value (between 15 …

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Article

Is Mapping of Complex Fractionated Electrograms Obsolete?

… by Thomas Lewis in 192011 before being superseded by the multiple wavelet hypothesis of Moe and Abildskov in 1959. 12 … or strands of refractory tissue, and each of the daughter wavelets may now be considered an independent offspring. … of the atria during AF was mapped. 14 These studies showed multiple wavelets wandering around natural anatomical …

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Article

Body Surface Mapping to Guide Atrial Fibrillation Ablation

… visualisation of AF-driving substrate in the form of multiple wavelets and reentrant drivers. Prior knowledge of the main … for Atrial Fibrillation From the previous investigations, multiple atrial wavelets, macroreentries and localised …

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Article

Source Determination in Atrial Fibrillation

… 1900s include focal automaticity, organised re-entry or multiple re-entrant wavelets. 6-9 Technological advances since then have allowed … triggers may be the dominant mechanism in paroxysmal AF, multiple mechanisms often coexist in patients with persistent …

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Article

Body Surface Electrocardiographic Mapping for Non-invasive Identification of Arrhythmic Sources

… used in the reconstruction of non-invasive maps using multiple torso electrodes have been previously described. 2 … epicardial RV activation is caused by the coalescence of multiple quick sequential breakthroughs. On the LV, … biatrial activation patterns during AF included multiple wavelets (1-5 and most commonly two wavelets) in 92 %, …

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Article

Relationship Between Obstructive Sleep Apnoea and AF

… Common to AF and Obstructive Sleep Apnoea OSA and AF share multiple risk factors. Obesity seems to be the metabolic … Factor for AF in Patients with Heart Failure? Although multiple studies have assessed the association between OSA … of AF: the multiple wavelet theory where multiple wavelets of activation coalesce and spread across the atrium; …

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Article

Pharmacological Tests in Atrial Fibrillation Ablation

… the left atrium (LA). 4 Large observational studies and multiple randomised-controlled trials have demonstrated that … postulated that AF resulted from the co-existence of multiple independent wavelets propagating randomly throughout the left and right …

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Article