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Author(s):
Robert H Anderson
,
Jill PJM Hikspoors
,
Justin T Tretter
,
et al
Added:
2 years ago
Author(s):
Ahmed M Al-Kaisey
,
William Figgett
,
Joshua Hawson
,
et al
Added:
11 months ago
Author(s):
Cristina E Molina
,
Jordi Heijman
,
Dobromir Dobrev
Added:
3 years ago
Optimal cardiac function depends on appropriate rate and force of contraction, with specific cardiac regions having developed particular beat-to-beat properties depending on their individual functions. For example, isovolumetric contraction time is shorter in the right ventricle (RV) than in the left ventricle (LV). At the cellular level, cardiac function is regulated by regional cardiomyocyte…
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Ventricular Tachycardia Isthmus
Author(s):
Ruairidh Martin
,
Meleze Hocini
,
Michel Haissaguerre
,
et al
Added:
3 years ago
Article
Author(s):
Sebastian Clauss
,
Moritz F Sinner
,
Stefan Kääb
,
et al
Added:
3 years ago
Atrial fibrillation (AF) is the most common arrhythmia experienced in clinical practice, and is responsible for significant morbidity and mortality.1 It affects more than 6 million people in Europe.1 The lifetime risk of developing AF after the age of 40 is approximately 25 %.1 AF is a major public health burden as it is associated with an increased risk of stroke by fivefold, dementia by twofold…
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Author(s):
Dominik Linz
,
Sander Verheule
,
Aaron Isaacs
,
et al
Added:
2 years ago
Author(s):
Nabil El-Sherif
,
Gioia Turitto
,
Mohamed Boutjdir
Added:
3 years ago
Since its initial description by Jervell and Lange-Nielsen in 1957,1 congenital long QT syndrome (LQTS) has been the most investigated cardiac ion channelopathy. A prolonged QT interval on the surface ECG is a surrogate measure of prolonged ventricular action potential duration (APD).
Congenital as well as acquired alterations in certain cardiac ion channels can affect their currents in such a…
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Author(s):
Rikke Esberg Kirkfeldt
,
Jens Brock Johansen
,
Jens Cosedis Nielsen
Added:
3 years ago
Cardiac implantable electronic device (CIED) therapy is effective and safe. However, infections related to CIED treatment may have devastating consequences, causing significant morbidity, mortality and generating considerable healthcare costs.1–6 Temporal trends in CIED treatment indicate a disproportional increase in CIED infections relative to implantation rates.1,7,8 Reasons for this trend are…
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Long QT Syndrome Modelling
Author(s):
Luca Sala
,
Massimiliano Gnecchi
,
Peter J Schwartz
Added:
3 years ago
Article
Author(s):
David J Sprenkeler
,
Marc A Vos
Added:
3 years ago
The concept of post-extrasystolic potentiation (PESP), which describes the phenomenon of increased contractility of the beat following an extrasystole, has intrigued physiologists and clinicians for more than 120 years. Since its first description in 1885 by Oskar Langendorff,1 PESP has become a widely debated concept, not only for its fundamental basis but also because of the potential…
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