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Author(s): Simon Ermakov , Melvin Scheinman Added: 3 years ago
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited cardiomyopathy characterised by progressive replacement of the ventricular myocardium by fibrofatty tissue.1 Patients with the disease are predisposed to ventricular arrhythmias, heart failure and sudden cardiac death. Pathophysiology ARVC has a strong genetic basis with most disease variants displaying an autosomal dominant… View more

Standards & Guidelines

Heart Failure
Author(s): David J Callans Added: 3 years ago
Premature ventricular contractions (PVCs) are very common cardiac arrhythmias, detected on up to 75% of Holter monitors of ambulatory patients.1 Although PVCs in the setting of advanced structural heart disease have independent negative prognostic implications,2 the majority of PVCs are quite benign, associated with neither symptoms nor signals of future harm. For an important minority, PVCs… View more

Heart Failure
Team Management of the Ventricular Tachycardia Patient
Author(s): Pok Tin Tang , Duc H Do , Anthony C Li , et al Added: 3 years ago
Ventricular arrhythmias remain a major contributor to cardiac morbidity and mortality worldwide, despite ongoing research and implementation of novel therapeutic interventions. Modern management of patients with ventricular arrhythmias requires a multidisciplinary team approach, especially in complex presentations with a background of multiple medical comorbidities.1,2 Such teams may include… View more

Electrophysiology & Arrhythmia
ESC 23: COP-AF: Colchicine for Perioperative AF
Author(s): David Conen Added: 7 months ago
ESC 2023 — Dr David Conen (McMaster University, CA) joins us onsite for a short interview focussing on the findings from the COP-AF trial (NCT03310125). COP-AF (Population Health Research Institute) aimed to assess if oral colchicine reduced the incidence of perioperative atrial fibrillation and myocardial injury after non-cardiac surgery in patients undergoing major thoracic surgery. 3209… View more

Electrophysiology & Arrhythmia
Author(s): Jeffrey J Hsu , Ali Nsair , Jamil A Aboulhosn , et al Added: 3 years ago
Monomorphic ventricular arrhythmias (MMVA) are not uncommon in athletes,1,2 yet their presence appropriately raises concern among practitioners for possible increased risk of sudden cardiac death (SCD) during sports activity and competition. While all MMVA detected in athletes warrant further evaluation,1 a majority of MMVA in this population are likely to be benign. In some instances of so… View more

Heart Failure

Electrophysiology & Arrhythmia
Author(s): Amit J Thosani , Paul Gerczuk , Emerson Liu , et al Added: 3 years ago
Atrial fibrillation (AF) is the most common cardiac arrhythmia worldwide. In 2010, the prevalence of AF in the US was estimated at 5.9 million.1 The decision to pursue treatment to maintain sinus rhythm is driven by disabling symptoms related to AF; including palpitations, dyspnoea, fatigue, stroke and congestive heart failure. Percutaneous catheter-based ablation is an established therapy for… View more

Electrophysiology & Arrhythmia
Defibrillation Threshold Testing: Current Status
Author(s): Justin Hayase , Duc H Do , Noel G Boyle Added: 3 years ago
The ICD is an important therapy for both primary and secondary prevention of sudden cardiac death in selected patients. The role for defibrillation threshold (DFT) testing either intraoperatively or postoperatively has changed significantly over the past few decades, and it is no longer routinely recommended in patients undergoing left-sided transvenous ICD implantation.1–7 The definition of the… View more

Electrophysiology & Arrhythmia
The Cutting Edge of Atrial Fibrillation Ablation
Author(s): Maya S Verma , Maria Terricabras , Atul Verma Added: 2 years ago

Electrophysiology & Arrhythmia
Author(s): Konstantinos C Siontis , Hakan Oral Added: 3 years ago
Advanced catheter-based technologies employed for the ablation of symptomatic atrial fibrillation (AF) have revolutionised the management of this common sustained arrhythmia. In the late 1990s, premature depolarisations originating from the myocardial sleeves within the pulmonary veins were recognised to initiate AF. This landmark discovery rendered pulmonary vein isolation (PVI) as the… View more

Imaging & Diagnostics

Electrophysiology & Arrhythmia
Author(s): Rahul K Mukherjee , Louisa O’Neill , Mark D O’Neill Added: 3 years ago
Recurrent ventricular tachycardia (VT) in patients who have an implantable cardioverter-defibrillator (ICD) with subsequent shocks is associated with reduced quality of life and an adverse prognosis. Pharmacological treatments are associated with significant side-effects. Catheter ablation has been used to reduce the number of ICD therapies in patients with ischaemic and non-ischaemic… View more

Electrophysiology & Arrhythmia