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Author(s): Eyal Nof , William G Stevenson , Roy John Added: 3 years ago
Sustained ventricular tachycardia (VT) and ventricular fibrillation (VF) are typically a manifestation of significant structural heart disease and often associated with a high risk of sudden cardiac death. Implantable cardioverter defibrillators (ICDs) remain the mainstay of therapy for prevention of sudden cardiac death associated with these arrhythmias.1 However, ICDs treat the arrhythmia after… View more

Electrophysiology & Arrhythmia
Author(s): Khang-Li Looi , Anthony SL Tang , Sharad Agarwal Added: 3 years ago
Heart failure (HF) is a growing and major health burden in western countries. The prevalence of HF is estimated at 1–2 % in the western world, and the incidence approaches 5–10 per 1,000 persons per year.1Cardiac resynchronisation therapy (CRT) has been shown in multiplestudies to improve HF symptoms, quality of life and improve survivals.2–6The two landmark studies, Comparison of Medical Therapy… View more

Heart Failure

Electrophysiology & Arrhythmia
Author(s): Jan M Griffin , Jason N Katz Added: 3 years ago
Prior to the widespread availability of left ventricular assist devices (LVADs), many end-stage heart failure patients were forced to fight over scarce transplant resources or face the reality of impending death. For those considered transplant-ineligible, due to medical or psychosocial factors, symptom palliation and end-of-life care were the only available options. This all changed dramatically… View more

Electrophysiology & Arrhythmia
Author(s): Josef Kautzner , Petr Peichl Added: 3 years ago
Ventricular fibrillation (VF) is a complex arrhythmia that leads invariably to cardiac arrest. Its mechanisms remain largely unclear. Similar to atrial fibrillation, the mother rotor hypothesis is one plausible alternative.1,2 In larger animals, some authors reported that the dominant frequency of VF could be recorded at a junction of the left ventricular posterior wall and the septum.3-6 Others… View more

Electrophysiology & Arrhythmia

MI/ACS
Contemporary Management of Complex Ventricular Arrhythmias
Author(s): Benedict Wiles , Anthony C Li , Michael C Waight , et al Added: 1 year ago

Electrophysiology & Arrhythmia
Arrhythmogenic Mitral Valve Prolapse
Author(s): Theofanis George Korovesis , Paraskevi Koutrolou-Sotiropoulou , Demosthenes G Katritsis Added: 1 year ago

Imaging & Diagnostics

Electrophysiology & Arrhythmia
Long-term Outcomes of Ventricular Tachycardia Ablation in Different Types of Structural Heart Disease
Author(s): Jackson J Liang , Pasquale Santangeli , David J Callans Added: 3 years ago
Ventricular tachycardia (VT) is a significant cause of morbidity and mortality in patients with structural heart disease (SHD). While implantable cardioverter-defibrillators (ICDs) have been shown to be effective in preventing sudden death due to ventricular arrhythmias, they are not able to prevent recurrent VT episodes. Antiarrhythmic drugs (AADs) have some demonstrated efficacy in preventing… View more

Vascular Disease and Surgery

Heart Failure
Diagnosis of Conduction System Capture Versus Myocardial-only Capture
Author(s): Marek Jastrzębski Added: 2 years ago

Imaging & Diagnostics

Electrophysiology & Arrhythmia
Author(s): Rakesh Gopinathannair , Benjamin C Salgado , Brian Olshansky Added: 3 years ago
Heart rate and blood pressure are tightly regulated by autonomic control to effect adequate blood flow as needed. This regulatory process breaks down when the vasovagal reflex is activated. Profound, but brief, circulatory collapse manifests as bradycardia (cardioinhibitory response) and/or hypotension (vasodepressor response) and/or altered cerebral autoregulation, resulting in transient loss of… View more

Electrophysiology & Arrhythmia
Hybrid Catheter-Based and Surgical Techniques for Ablation of Ventricular Arrhythmias
Author(s): Fouad Khalil , Konstantinos C Siontis , Gabor Bagameri , et al Added: 3 years ago
Catheter-based ablation has been a well-established tool in the treatment of ventricular tachycardia (VT). However, the effectiveness of catheter ablation may be limited by its ability to access sites of arrhythmogenic tissue and achieve adequate lesion size in target areas without risking collateral damage. Antiarrhythmic surgery would be an effective alternative in such situations. Despite the… View more

Electrophysiology & Arrhythmia