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Author(s):
Jorge E Romero
,
Dan L Li
,
Ricardo Avendano
,
et al
Added:
3 years ago
Brugada syndrome (BrS), one of the most common causes of sudden cardiac death (SCD) in normal structural heart individuals, is a young entity in modern medicine. BrS was first characterised in 1992 by Brugada et al. as a distinct syndrome with “right bundle branch block, persistent ST elevation in precordial leads V1 to V2–3 and sudden cardiac death”.1 The true prevalence of BrS is not clearly…
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Author(s):
Shohreh Honarbakhsh
,
Rui Providencia
,
Pier D Lambiase
Added:
3 years ago
Brugada syndrome (BrS) remains one of the most common inherited channelopathies associated with an increased risk of sudden cardiac death (SCD), with a worldwide prevalence of approximately 0.05%.1–3 It is accepted that appropriate utilisation of the ICD in high-risk patients with aborted SCD and haemodynamically compromising arrhythmias is life-saving. However, there remains a lack of consensus…
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Author(s):
Rahul K Mukherjee
,
Louisa O’Neill
,
Mark D O’Neill
Added:
3 years ago
Recurrent ventricular tachycardia (VT) in patients who have an implantable cardioverter-defibrillator (ICD) with subsequent shocks is associated with reduced quality of life and an adverse prognosis. Pharmacological treatments are associated with significant side-effects. Catheter ablation has been used to reduce the number of ICD therapies in patients with ischaemic and non-ischaemic…
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Author(s):
Venkatesh Ravi
,
Jeffrey Winterfield
,
Jackson J Liang
,
et al
Added:
1 year ago
Author(s):
Satoshi Higa
,
Li-Wei Lo
,
Shih-Ann Chen
Added:
3 years ago
Catheter ablation of AF has become an established therapy and may have the potential to cure this most commonly encountered sustained arrhythmia. Previous studies have demonstrated that pulmonary veins (PVs) are a major source of the ectopic beats that initiate AF. PV isolation in patients with symptomatic paroxysmal AF refractory to antiarrhythmic drugs is effective; however, it is difficult to…
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Author(s):
Brenton S Bauer
,
Anthony C Li
,
Jason S Bradfield
Added:
3 years ago
Ventricular arrhythmias (VA) are commonly associated with structural heart disease and have substantial impact on patient outcomes and health system costs. Within the realm of cardiomyopathy (CM), there has been substantial progress with respect to ischaemic CM (ICM) in the understanding of infarct related scar biology and scar-mediated ventricular tachycardia (VT).
This has led to interventions…
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Author(s):
Benjamin Berte
,
Katja Zeppenfeld
,
Roderick Tung
Added:
3 years ago
Accurate substrate characterisation is important for depicting scar-related re-entrant tachycardia to optimise ablation targets and strategies. The underlying substrate can be analysed using electrogram (EGM) characteristics, such as low voltage, local abnormal voltage activity (LAVA), evoked potentials or late potentials, conduction analysis in sinus rhythm or differential pacing, or using…
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Author(s):
Saagar Mahida
,
Frédéric Sacher
,
Nicolas Derval
,
et al
Added:
3 years ago
Atrial fibrillation (AF) is the most commonly encountered arrhythmia in clinical practice. The discovery that pulmonary veins (PV) play a prominent role in the pathogenesis of AF has revolutionised the management of AF. PV isolation has become the most widely used technique for treatment of paroxysmal AF. Since the initial discovery implicating PVs in AF pathogenesis, the mechanistic link between…
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Author(s):
Pok Tin Tang
,
Duc H Do
,
Anthony C Li
,
et al
Added:
3 years ago
Ventricular arrhythmias remain a major contributor to cardiac morbidity and mortality worldwide, despite ongoing research and implementation of novel therapeutic interventions. Modern management of patients with ventricular arrhythmias requires a multidisciplinary team approach, especially in complex presentations with a background of multiple medical comorbidities.1,2 Such teams may include…
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Author(s):
Pasquale Vergara
,
Savino Altizio
,
Giulio Falasconi
,
et al
Added:
2 years ago