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Author(s): William Eysenck , Magdi Saba Added: 3 years ago
Sir James Mackenzie, famous for describing the first mechanistic insights into AF in 1902 using his polygraph, also reported that AF was present in 80–90% of patients who had congestive heart failure (HF) in 1920.1 Today, the conditions are the two ‘epidemics’ of cardiovascular disease.2 They are dominating cardiovascular care and, with increasing longevity, they will become more prevalent and… View more
Author(s): Konstantinos C Siontis , Hakan Oral Added: 3 years ago
Advanced catheter-based technologies employed for the ablation of symptomatic atrial fibrillation (AF) have revolutionised the management of this common sustained arrhythmia. In the late 1990s, premature depolarisations originating from the myocardial sleeves within the pulmonary veins were recognised to initiate AF. This landmark discovery rendered pulmonary vein isolation (PVI) as the… View more
Author(s): Tauseef Akhtar , Ronald Berger , Joseph E Marine , et al Added: 3 years ago
AF is a common and clinically impactful arrhythmia. Given both the association of AF with aging and the increasing number of elderly people in the general population, it follows that many AF patients are of advanced age. The management of AF in the geriatric population is associated with several challenges, including multiple comorbidities, increased toxicity of antiarrhythmic drugs (AAD), an… View more
Author(s): Rakesh Latchamsetty , Fred Morady Added: 3 years ago
Catheter ablation of AF has shown steady growth over the past two decades with a nearly 15 % annual increase in the US.1 This growth can be attributed in large part to four factors: an increase in operators and institutions performing the procedure;2 a steady rise in AF prevalence, which is predicted to reach 12 million in the US by 2030;3 a larger spectrum of AF patients with more complex atrial… View more
Author(s): Vishal Vyas , Pier D Lambiase Added: 3 years ago
Worldwide obesity has reached pandemic proportions with more than 1.9 billion adults classed as overweight in 2016, of which 650million were obese.1 Since it is a major modifiable risk factor for so many cardiovascular diseases, it is no surprise there has been an exponential increase in cases of AF coinciding with the rise in obesity. While there were an estimated 8.8 million cases of AF in 2010… View more
Author(s): A John Camm Added: 3 years ago
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, occurring in 1–2 % of the general population and is increasingly prevalent in older people, occurring in about 10 % of over 80 year olds.1 AF is associated with a variety of cardiovascular conditions. The arrhythmia is associated with a five-fold rise in stroke risk and frequently coexists with heart failure, both leading… View more
Author(s): Alex Baher , Nassir F Marrouche Added: 3 years ago
AF is the most common rhythm disorder. It is estimated AF will affect 6–12 million Americans by 2050 and 17.9 million Europeans by 2060.1–4 AF is responsible for significant morbidity, mortality and healthcare costs.5–7 Heart failure with reduced ejection fraction (HFrEF) is also a rising epidemic that will afflict over 8 million Americans by 2030.8 AF is common in patients with HFrEF9,10 and… View more
Author(s): George D Katritsis , Vishal Luther , Prapa Kanagaratnam , et al Added: 3 years ago
The introduction of cardiac electroanatomic mapping systems in the mid-1990s has permitted investigators to record intracardiac electrograms (EGMs) with accurate spatial localisation in 3D.1 These 3D mapping systems have enabled the display of the cardiac chambers as an anatomical shell upon which voltage, or activation, information can be displayed. Most commonly, colour is used to represent the… View more
Author(s): Seigo Yamashita , Ashok J Shah , Saagar Mahida , et al Added: 3 years ago
Catheter ablation therapy has been widely used for rhythm control in patients with atrial fibrillation(AF).1 Since the first report in 1994,2 several interventional techniques have been proposed for AF, including replication of the surgical Maze,2 targeting pulmonary vein (PV) foci,3 segmental ostial and circumferential PV isolation,4,5 ganglionated plexi ablation,6 linear lesions in the left… View more
Author(s): Stephen P Page , Mehul Dhinoja Added: 3 years ago
Over the last 30 years, the role of catheter ablation for treating a wide range of arrhythmias has increased dramatically. The electrophysiological substrates of the more straightforward arrhythmias (such as atrio-ventricular reciprocating tachycardia and atrio-ventricular nodal re-entry tachycardia) have now been well defined and excellent long-term success rates can be achieved at minimal risk… View more