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Atrial Fibrillation Structural Substrates: Aetiology, Identification and Implications
Author(s): Ahmed M Al-Kaisey , Ramanathan Parameswaran , Jonathan M Kalman Added: 3 years ago
AF is the most common sustained cardiac rhythm disorder and is associated with increased morbidity and mortality. Since the first description of AF initiation by triggers from pulmonary veins sleeves, pulmonary vein isolation (PVI) has become the standard ablation strategy in patients with AF.1 However, freedom from the arrhythmia, particularly in non-paroxysmal AF, remains suboptimal, and it is… View more

Electrophysiology & Arrhythmia
Obesity and AF
Author(s): Ahmed M Al-Kaisey , Jonathan M Kalman Added: 2 years ago

Electrophysiology & Arrhythmia

Prevention & Chronic Conditions
Author(s): Amir S Jadidi , Thomas Arentz Added: 3 years ago
Adecade after its first description as ‘the electrophysiological substrate’ of atrial fibrillation,1 mapping complex fractionated atrial electrogram (CFAE) as an ablation target for atrial fibrillation (AF) remains highly controversial. Early high-density mapping studies of induced AF in humans revealed distinct mechanisms that underlie electrogram fractionation: collision areas of distinct… View more

Imaging & Diagnostics

Electrophysiology & Arrhythmia
Cardiac MRI to Manage Atrial Fibrillation
Author(s): Yan Zhao , Lilas Dagher , Chao Huang , et al Added: 3 years ago
AF is a common arrhythmia in clinical practice, with a prevalence of 2.7–6.1 million that is expected to rise to 5.6–12 million by 2050 in the US alone.1,2 Patients with AF have an increased risk of stroke and mortality and a decreased quality of life.3 In addition, management of AF increases the cost of healthcare.4,5,6 The mechanisms of AF are complex and are associated with electric and… View more

Imaging & Diagnostics
Author(s): Jean-Baptiste Gourraud , Jason G Andrade , Laurent Macle , et al Added: 3 years ago
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia observed in clinical practice, occurring in approximately 2 % of the general population.1–3 A progressive increase in both the prevalence and incidence of AF has been demonstrated in recent years, defining AF as a major economic and public health issue.1 The identification of sites of AF initiation and/or maintenance within… View more

Electrophysiology & Arrhythmia

Prevention & Chronic Conditions
Author(s): Domenico G Della Rocca , Sanghamitra Mohanty , Chintan Trivedi , et al Added: 3 years ago
AF is the most common sustained arrhythmia, and carries an increased risk of cardiovascular and cerebrovascular complications. The latest estimates on the prevalence of AF portray an alarming scenario, with a steep increase in the number of people developing AF and prediction that the number affected will more than double in the next 40 years.1 Among the strategies to restore and maintain sinus… View more

Electrophysiology & Arrhythmia
Author(s): Marius Andronache , Nikola Drca , Graziana Viola Added: 3 years ago
AF is the most common sustained cardiac arrhythmia in clinical practice. It is associated with increased risk of stroke and heart failure (HF), and is a significant global health challenge.1 Catheter ablation procedures, which isolate the pulmonary veins (PV) from the left atrium and prevent AF initiation, are effective and safe treatment options, and have emerged as the preferred rhythm control… View more

Electrophysiology & Arrhythmia
Atrial Myopathy Underlying Atrial Fibrillation
Author(s): Harold Rivner , Raul D Mitrani , Jeffrey J Goldberger Added: 3 years ago
AF is the most common sustained cardiac rhythm disturbance.1 Worldwide, there is an estimated 33.5 million people with AF as of 2010.2 While there are multiple estimates, the yearly incidence in the US is expected to grow, for example, from 1.2 million cases in 2010 to 2.6 million cases in 2030 and upwards of 6–12 million cases by 2050.1,3 It is associated with increased morbidity and mortality4… View more

Imaging & Diagnostics
Author(s): Ian Mann , Belinda Sandler , Nick WF Linton , et al Added: 3 years ago
The discovery of focal ectopy in the pulmonary veins (PVs) initiating AF1 has resulted in electrical isolation of the PVs forming the mainstay of current treatment strategies. Success rates from PV isolation (PVI) for patients with paroxysmal AF (PAF) are approximately 70–75%. However, PVI is significantly less effective for those with persistent AF, in whom many studies quote single-procedure… View more

Electrophysiology & Arrhythmia
Author(s): Rakesh Latchamsetty , Fred Morady Added: 3 years ago
Catheter ablation of AF has shown steady growth over the past two decades with a nearly 15 % annual increase in the US.1 This growth can be attributed in large part to four factors: an increase in operators and institutions performing the procedure;2 a steady rise in AF prevalence, which is predicted to reach 12 million in the US by 2030;3 a larger spectrum of AF patients with more complex atrial… View more

Electrophysiology & Arrhythmia