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Author(s): Jonathan S Steinberg , David Slotwiner Added: 3 years ago
Electrical Remodelling Evidence Supporting Atrial Remodelling The concept of electrical remodelling was first introduced in 1995 simultaneously by Wijffels et al.1 and Morillo et al.2 who demonstrated that once sustained atrial fibrillation (AF) was induced in goats, or rapid atrial pacing was performed in dogs, physiological changes occurred that favoured the maintenance of AF.3 This led to the… View more
Author(s): Sebastian Clauss , Moritz F Sinner , Stefan Kääb , et al Added: 3 years ago
Atrial fibrillation (AF) is the most common arrhythmia experienced in clinical practice, and is responsible for significant morbidity and mortality.1 It affects more than 6 million people in Europe.1 The lifetime risk of developing AF after the age of 40 is approximately 25 %.1 AF is a major public health burden as it is associated with an increased risk of stroke by fivefold, dementia by twofold… View more
Author(s): Andreas Metzner , Erik Wissner , Tina Lin , et al Added: 3 years ago
Atrial fibrillation (AF) is the most common cardiac arrhythmia affecting 1.5–2 % of the general population.1 In the current clinical guidelines, catheter ablation is recommended in addition to drug-based antiarrhythmic therapy for patients suffering from symptomatic, drugrefractory AF. However, catheter ablation, if performed at an experienced centre, may also serve as first-line therapy in… View more
Author(s): Karl-Heinz Kuck , Andreas Metzner Added: 3 years ago
Catheter-based ablation of atrial fibrillation (AF) is an established treatment option for symptomatic patients who are refractory to drug-based treatment, as implemented in the latest guidelines for the management of AF.1 The accepted and recommended cornerstone of all ablation strategies for AF is electrical isolation of the pulmonary veins (PV).2 However, in addition to PV isolation (PVI),… View more
Author(s): Vishal Vyas , Pier D Lambiase Added: 3 years ago
Worldwide obesity has reached pandemic proportions with more than 1.9 billion adults classed as overweight in 2016, of which 650million were obese.1 Since it is a major modifiable risk factor for so many cardiovascular diseases, it is no surprise there has been an exponential increase in cases of AF coinciding with the rise in obesity. While there were an estimated 8.8 million cases of AF in 2010… View more
Author(s): Tim Betts Added: 2 years ago
Global Substrate Mapping and Targeted Ablation with Novel Gold-Tip Catheter in De Novo Persistent AF View more
Author(s): George D Katritsis , Hugh Calkins Added: 3 years ago
Over the past decades catheter ablation of atrial fibrillation (AF) has evolved from being a largely experimental procedure to a well-established therapeutic option for certain patients with AF.1–4 Currently the backbone of most catheter ablation techniques is to target the pulmonary veins (PVs) in order to achieve their electrical isolation and maintain sinus rhythm (SR).1 Additional techniques… View more
Author(s): Ling Zhang , Yuemei Hou , Sunny S Po Added: 3 years ago
Atrial fibrillation(AF) is the most frequently encountered arrhythmia in clinical practice and has become an emerging epidemic. AF is associated with increased cardiovascular mortality and morbidy such as stroke.1–3 Over 2.3 million people in the US are affected by AF: it is estimated that AF will affect more than 15 million Americans by 2050.3 The traditional risk factors implicated in the… View more
Author(s): A John Camm Added: 3 years ago
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, occurring in 1–2 % of the general population and is increasingly prevalent in older people, occurring in about 10 % of over 80 year olds.1 AF is associated with a variety of cardiovascular conditions. The arrhythmia is associated with a five-fold rise in stroke risk and frequently coexists with heart failure, both leading… View more
Author(s): Tim Betts Added: 2 years ago
Global Substrate Mapping and Targeted Ablation with Novel Gold-Tip Catheter in De Novo Persistent AF View more