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PFA Safety Profile Assessed in Over 40,000 Patients
Added: 3 months ago Source:  Radcliffe Cardiology
Pulsed field ablation (PFA) is an emerging energy source for atrial fibrillation (AF) ablation, noted for its potential safety benefits, including a lower risk of injury to surrounding tissues. A large, real-world study has now provided extensive data on the safety of this technology in a broad patient population.¹Mechanism of ActionPFA utilises pulsed electric fields to create pores in cell… View more

Electrophysiology & Arrhythmia
Pentaspline PFA Safety Profile in 40,000+ Patients
Added: 3 months ago Source:  Arrhythmia Academy
Pulsed field ablation (PFA) is an emerging energy source for atrial fibrillation (AF) ablation, noted for its promising safety profile. A large, real-world study, MANIFEST-US, has provided extensive data on the safety and utilisation of the pentaspline PFA catheter in the United States.¹Mechanism of ActionPFA is a non-thermal ablation modality that uses pulsed electric fields to create lesions… View more

Electrophysiology & Arrhythmia

Prevention & Chronic Conditions
Durability of Pulsed Field Ablation Lesions
Author(s): Kars Neven , Anna Füting , Stefan Hartl , et al Added: 7 months ago

Electrophysiology & Arrhythmia
EHRA 2026: ULYSSES – Ultrasound-Guided Venous Access for Safer AF Ablation
Author(s): David Schaack Added: 3 weeks ago
EHRA 2026 — Dr David Schaack (CCB am Markus Hospital, Frankfurt am Main, Germany) joins us to discuss findings from the ULYSSES trial, evaluating whether ultrasound-guided venous puncture reduces access site complications in patients undergoing atrial fibrillation ablation.This investigator-initiated, prospective, randomised multicentre trial enrolled 1,075 patients with AF or left atrial… View more

Electrophysiology & Arrhythmia
EHRA 2026: Real-World Mortality Outcomes With PFA vs Thermal Ablation
Author(s): Roland R Tilz Added: 4 weeks ago
EHRA Congress 2026 – Prof Roland Tilz (University Hospital Schleswig-Holstein, Lübeck, DE) presents the findings from the TiFFANY-AF study, a retrospective observational analysis evaluating real-world mortality outcomes associated with pulsed field ablation compared with thermal ablation techniques — radiofrequency and cryoballoon — for atrial fibrillation.Drawing on a decade of data from the US… View more

Electrophysiology & Arrhythmia
Job title: Assistant Director of the Cardiac Non-invasive Laboratory
Temperature-controlled Versus Conventional Ablation Catheters for PVI in AF
Author(s): Benjamin Clay , Balamrit S Sokhal , Sarah Zeriouh , et al Added: 1 year ago

Electrophysiology & Arrhythmia
Chronic EIVOM Effects on PVI and Mitral Isthmus Block
Author(s): Ling-cong Kong , Tian Shuang , Yu-min Sun , et al Added: 5 months ago

Electrophysiology & Arrhythmia
Optimized Pacing Eases oHCM Symptoms in EMORI-HCM Trial
Added: 3 months ago Source:  Radcliffe Cardiology
For patients with symptomatic obstructive hypertrophic cardiomyopathy (oHCM), the net effect of right ventricular pacing (RVP) has been variable, as it can reduce the left ventricular outflow tract gradient (LVOTg) but may also decrease cardiac output.¹ The EMORI-HCM trial investigated whether electromechanically optimising the atrio-ventricular delay (AVD) could allow RVP to achieve a consistent… View more

Electrophysiology & Arrhythmia

Heart Failure
Nanosecond PFA Noninferior to RFA for Paroxysmal AF
Added: 5 months ago Source:  Radcliffe Cardiology
A novel nanosecond pulsed field ablation (nsPFA) system has demonstrated noninferior efficacy and comparable safety to conventional ablation index (AI)-guided radiofrequency ablation (RFA) for treating paroxysmal atrial fibrillation (AF), according to results from the InsightPFA trial.¹ The study also highlights that the procedure can be performed under conscious sedation, potentially… View more

Electrophysiology & Arrhythmia