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Author(s): John M Miller Added: 3 years ago
The Electrocardiogram In the entire realm of his work, Dr Josephson’s greatest love was the simple electrocardiogram (ECG). His discernment, based on the ECG, into the patient’s history and disease processes was legendary. Among the more important and insightful contributions he made to our understanding of heart disease and arrhythmias from the ECG are: observations of alternating preexcitation… View more
Author(s): Ashok J Shah , Meleze Hocini , Patrizio Pascale , et al Added: 3 years ago
The structural and/or functional abnormality of the cardiac electrovascular system is the most common cause of world mortality accounting for 29.0 % of deaths, followed by infectious diseases (16.2 %) and cancers (12.6 %) (WHO 2008 report). 1 Abnormalities in the cardiac electrical system (arrhythmias and sudden death) and/or mechanical function (heart failure) constitute one of the major causes… View more
Author(s): Jackson J Liang , Yasuhiro Shirai , Aung Lin , et al Added: 3 years ago
Idiopathic ventricular arrhythmias (VAs) are comprised of ventricular premature depolarisations, non-sustained ventricular tachycardia (VT)and rarely sustained VT, and these typically occur in the absence of structural heart disease. In general, idiopathic VAs tend to have a benign prognosis, although a high burden of VAs can result in left ventricular (LV) systolic dysfunction and cardiomyopathy… View more
Author(s): Demosthenes G Katritsis , Hein J Wellens , Mark E Josephson Added: 3 years ago
In 1941, Mahaim and Winston described the histology of anomalous connections that arise from the AV node and insert into the right ventricle.1 This was the first description of nodoventricular or so-called Mahaim accessory pathways. Accessory pathways with decremental conduction properties that connected the atrium to the right bundle branch (RBB) were subsequently mapped mainly at the lateral… View more
Author(s): Nikolaos Fragakis Added: 3 years ago
Dear Sir, I read with great interest the review article ‘Mahaim Accessory Pathways’ by D. Katritsis, et al.,1 in a past issue of Arrhythmia & Electrophysiology Review (AER 6(1):29-32). In this concise paper a systematic approach to electrophysiological diagnosis and differential diagnosis of these rare, but characteristic, pathways is presented. As the authors point out, pathways with Mahaim… View more
Author(s): David J Callans Added: 3 years ago
Premature ventricular contractions (PVCs) are very common cardiac arrhythmias, detected on up to 75% of Holter monitors of ambulatory patients.1 Although PVCs in the setting of advanced structural heart disease have independent negative prognostic implications,2 the majority of PVCs are quite benign, associated with neither symptoms nor signals of future harm. For an important minority, PVCs… View more
Author(s): Josef Kautzner , Petr Peichl Added: 3 years ago
Ventricular fibrillation (VF) is a complex arrhythmia that leads invariably to cardiac arrest. Its mechanisms remain largely unclear. Similar to atrial fibrillation, the mother rotor hypothesis is one plausible alternative.1,2 In larger animals, some authors reported that the dominant frequency of VF could be recorded at a junction of the left ventricular posterior wall and the septum.3-6 Others… View more