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Neuromodulation for Atrial Fibrillation
Author(s): Tolga Aksu , Jamario R Skeete , Henry H Huang Added: 1 year ago

Electrophysiology & Arrhythmia
Defining Left Bundle Branch Block Patterns in Cardiac Resynchronisation Therapy: A Return to His Bundle Recordings
Author(s): Roderick Tung , Gaurav A Upadhyay Added: 3 years ago
In 1970, Durrer et al. recorded the total excitation of the human heart with 870 electrodes and confirmed the first 10 ms of left ventricular (LV) activation as trifascicular in nature.1 The rapid and synchronous activation of the LV through the specialised His–Purkinje network is highly intricate and efficient, preserving normal physiological coupling between electrical excitation and mechanical… View more

Electrophysiology & Arrhythmia
Author(s): Dario DiFrancesco Added: 3 years ago
HCN4 (hyperpolarisation-activated, cyclic nucleotide gated 4) channels, the pore-forming α–subunits of ‘funny’ channels originally described in pacemaker cells of the sinoatrial node (SAN),1 are responsible for the early phase of diastolic depolarisation in these cells and are key determinants of pacemaker generation and control of heart rate.2–5 HCN4 channels are selectively expressed in the SAN… View more

Electrophysiology & Arrhythmia
Author(s): Pasquale Santangeli , Luigi Di Biase , Eloisa Basile , et al Added: 3 years ago
The number of invasive electrophysiological procedures is steadily increasing in Western countries, as techniques advance and the age of the population increases. Gender exerts a profound influence on the epidemiology, pathophysiology and clinical presentation of many cardiac rhythm disorders, and all these factors may affect the outcome of invasive electrophysiological procedures. Disturbingly,… View more

Demographic
Author(s): Ameeta Yaksh , Lisette JME van der Does , Eva AH Lanters , et al Added: 3 years ago
Cardiac arrhythmias during pregnancy pose a serious threat to the health of both mother and foetus. Women with established tachyarrhythmias, congenital heart defects or channelopathies have the highest risk for development of arrhythmias.1,2 They also develop de novo or occur in women without apparent heart diseases. Tachyarrhythmias, including both supraventricular and ventricular tachycardias,… View more

Electrophysiology & Arrhythmia

Prevention & Chronic Conditions
Implantable Cardiac Electronic Devices in the Elderly Population
Author(s): Wei-Yao Lim , Sandeep Prabhu Added: 3 years ago
The number of cardiac implantable electronic devices (CIED) has been increasing year-on-year.1 This, coupled with improvements in life expectancy,2 means that more elderly patients will meet the criteria for a CIED. National and international guidelines set out clear criteria and make recommendations for CIED use based on available evidence.3–6 However, the majority of clinical trials include few… View more

Electrophysiology & Arrhythmia
Cardiac Resynchronisation with Conduction System Pacing
Author(s): Fatima M Ezzeddine , Isaac G Leon , Yong-Mei Cha Added: 8 months ago

Electrophysiology & Arrhythmia
Author(s): David Hamon , Jane Taleski , Marmar Vaseghi , et al Added: 3 years ago
Orthotopic heart transplantation (OHT) is the most effective long-term therapy for end-stage heart disease, with implanted left ventricular assist devices (‘destination therapy’) as an alternative for selected patients. The denervation of the transplanted heart with complete loss of autonomic nervous system modulation, the use of immunosuppressant drugs, as well as the risk of allograft rejection… View more

Vascular Disease and Surgery

Electrophysiology & Arrhythmia
Conduction System Pacing for Cardiac Resynchronisation
Author(s): Parikshit S Sharma , Pugazhendhi Vijayaraman Added: 3 years ago

Electrophysiology & Arrhythmia
Physiology and Practicality of Left Ventricular Septal Pacing
Author(s): Luuk Heckman , Justin Luermans , Floor Salden , et al Added: 2 years ago

Electrophysiology & Arrhythmia