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Author(s):
George D Katritsis
,
Demosthenes G Katritsis
Added:
3 years ago
Implantable cardiac devices, such as pacemakers, are used to treat a number of heart conditions, especially those related to the electrical conduction system. Cardiac pacemakers are a well-established and effective therapy, and have been in use for more than 50 years.
The first pacemaker was implanted in a patient in October 1958 by Åke Senning in Stockholm, in cooperation with engineer Rune…
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Device-Based Approaches to Modulate the Autonomic Nervous System and Cardiac Electrophysiology
Author(s):
William J Hucker
,
Jagmeet P Singh
,
Kimberly Parks
,
et al
Added:
3 years ago
Article
Author(s):
Peter J Schwartz
Added:
3 years ago
Despite the clear improvements in clinical outcomes brought about by medical therapy with β-blockers, ACE inhibitors and aldosterone antagonists, as well as by device therapy with cardiac resynchronisation, many patients with chronic heart failure (HF) remain symptomatic despite optimal medical therapy. Symptomatic HF can have devastating consequences for the quality of life of individuals, and…
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Author(s):
Stavros Stavrakis
,
Sunny Po
Added:
3 years ago
There are numerous conglomerations of autonomic ganglia on the epicardial surface of the heart, known as ganglionated plexi (GP). These GP have been shown to play a significant role in different arrhythmias, including AF. As such, GP ablation has become an adjunctive procedure in the treatment of AF. This review will present the current data on the significance of GP in arrhythmogenesis and will…
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Stavros Stavrakis
Research Area(s) / Expertise:
Job title: Associate Professor of Medicine; Laureate Chair in Molecular Medicine; Vice Chief, Cardiovascular Section
Author
Author(s):
Yunqiu Jiang
,
Sunny S Po
,
Faris Amil
,
et al
Added:
3 years ago
Imbalance of the autonomic nervous system (sympathetic/parasympathetic) is known to contribute to the pathophysiology of multiple cardiovascular diseases, including AF, MI (and related ventricular arrhythmias) and heart failure. The concept of neuro-immune axis has been proposed to tightly integrate the brain–heart–periphery axis, which is characterised by various pathways of the anti…
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Philip Adamson
Job title: Medical Director
Author
Brian Olshansky
Research Area(s) / Expertise:
Job title: Emeritus Professor of Medicine
Author
Author(s):
Stavros Stavrakis
,
Sunny Po
Added:
3 years ago
Dear Sir,
We thank Dr Pachon for his interest in our manuscript.1 While we acknowledge that the concept of autonomic ablation for treatment of bradyarrhythmias was first proposed by Dr Pachon’s group,2,3 we would like to draw the reader’s attention to the methods of identifying the ganglionated plexi (GP). The original description by Dr Pachon’s group was based on Fast-Fourier Transform (FFT)…
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