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Author(s):
Raphael K Sung
,
Penelope A Boyden
,
Satoshi Higuchi
,
et al
Added:
2 years ago
Author(s):
Hongwu Chen
,
Kit Chan
,
Sunny S Po
,
et al
Added:
3 years ago
Ventricular tachycardia (VT) originating from the Purkinje system is the most common type of idiopathic left ventricular tachycardia (ILVT), especially among young Asians.1,2 It usually has a benign course. Research over the past two decades has deepened our understanding of the anatomy of the Purkinje system and the mechanisms of ILVT. This review focuses on the research history and anatomy of…
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Author(s):
Demosthenes G Katritsis
,
Mark E Josephson
Added:
3 years ago
Atrioventricular nodal reentrant tachycardia (AVNRT) denotes re-entry in the area of the AV node, and represents the most common regular arrhythmia in the human.1 Although several models have been proposed to explain the mechanism of the arrhythmia in the context of the complex anatomy and the anisotropic properties of the atrioventricular (AV) node and its atrial extensions (see Figure 1),2 the…
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Author(s):
Josef Kautzner
,
Petr Peichl
Added:
3 years ago
Ventricular fibrillation (VF) is a complex arrhythmia that leads invariably to cardiac arrest. Its mechanisms remain largely unclear. Similar to atrial fibrillation, the mother rotor hypothesis is one plausible alternative.1,2 In larger animals, some authors reported that the dominant frequency of VF could be recorded at a junction of the left ventricular posterior wall and the septum.3-6 Others…
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Author(s):
Laurent Roten
,
Matthew Daly
,
Patrizio Pascale
,
et al
Added:
3 years ago
With an ageing population and widespread use of implantable cardioverter-defibrillators, physicians are confronted with an increasing number of patients with symptomatic, drug-refractory ventricular tachycardia (VT). Catheter ablation is an important treatment option in the management of patients with structural heart disease and VT.1,2 In many patients, VT can be successfully ablated from the…
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Author(s):
Mohamed Abbas
,
Chris Miles
,
Elijah R Behr
Added:
1 year ago
Mahaim Accessory Pathways
Author(s):
Demosthenes G Katritsis
,
Hein J Wellens
,
Mark E Josephson
Added:
3 years ago
Article
Author(s):
Ethan R Ellis
,
Mark E Josephson
Added:
3 years ago
Cardiomyopathies are heterogeneous heart muscle disorders with a wide range of aetiologies and clinical manifestations. They are often defined by their causes (i.e. hypertension, prior myocardial infarction, valvular heart disease), although current major society definitions describe cardiomyopathy as the presence of abnormal myocardial structure and/or function in the absence of underlying…
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Author(s):
Eyal Nof
,
William G Stevenson
,
Roy John
Added:
3 years ago
Sustained ventricular tachycardia (VT) and ventricular fibrillation (VF) are typically a manifestation of significant structural heart disease and often associated with a high risk of sudden cardiac death. Implantable cardioverter defibrillators (ICDs) remain the mainstay of therapy for prevention of sudden cardiac death associated with these arrhythmias.1 However, ICDs treat the arrhythmia after…
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Author(s):
John M Miller
Added:
3 years ago
The Electrocardiogram
In the entire realm of his work, Dr Josephson’s greatest love was the simple electrocardiogram (ECG). His discernment, based on the ECG, into the patient’s history and disease processes was legendary. Among the more important and insightful contributions he made to our understanding of heart disease and arrhythmias from the ECG are: observations of alternating preexcitation…
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