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3 years ago
Brugada syndrome (BrS) is a cardiac disease caused by an inherited ion channelopathy. It was first described by the Brugada brothers in 19921 and is associated with a propensity to develop ventricular fibrillation (VF). Brugada syndrome is characterised by prominent J waves appearing as an ST segment elevation in the right precordial leads. In the latest guidelines, diagnosis of BrS constitutes…
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3 years ago
Brugada syndrome (BrS), one of the most common causes of sudden cardiac death (SCD) in normal structural heart individuals, is a young entity in modern medicine. BrS was first characterised in 1992 by Brugada et al. as a distinct syndrome with “right bundle branch block, persistent ST elevation in precordial leads V1 to V2–3 and sudden cardiac death”.1 The true prevalence of BrS is not clearly…
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3 years ago
Historical Precedents
Brugada syndrome (BrS) was first described more than 25 years ago as a clinical entity in people resuscitated from sudden cardiac death due to documented VF.1 The original 1992 case series described eight patients without apparent structural heart disease who all had VF associated with persistent coved ST-segment elevation in the right precordial leads.1 In 1996 this…
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3 years ago
General understanding of early repolarisation (ER) has dramatically changed in the last decade. For several years, ER has been considered a benign electrocardiographic (ECG) finding with high prevalence in the general population. Recently different studies have challenged this view and showed a significant association with life-threatening arrhythmias.1–5
In 2008 Haïssaguerre et al. first…
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