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Author(s): Tauseef Akhtar , Ronald Berger , Joseph E Marine , et al Added: 3 years ago
AF is a common and clinically impactful arrhythmia. Given both the association of AF with aging and the increasing number of elderly people in the general population, it follows that many AF patients are of advanced age. The management of AF in the geriatric population is associated with several challenges, including multiple comorbidities, increased toxicity of antiarrhythmic drugs (AAD), an… View more
Author(s): Konstantinos C Siontis , Hakan Oral Added: 3 years ago
Advanced catheter-based technologies employed for the ablation of symptomatic atrial fibrillation (AF) have revolutionised the management of this common sustained arrhythmia. In the late 1990s, premature depolarisations originating from the myocardial sleeves within the pulmonary veins were recognised to initiate AF. This landmark discovery rendered pulmonary vein isolation (PVI) as the… View more
Author(s): George Paxinos Added: 3 years ago
Dear Sir, I read with great interest the elegant article of Umbrain et al.1 on hybrid AF treatment in issue 6.4 of AER. It delineates in a comprehensive but succinct manner the technical problems and peculiarities of this promising approach. However, in my capacity as a general cardiologist and director of a primary care centre, I am very much concerned about the costs of such procedures. In the… View more
Author(s): Saagar Mahida , Frédéric Sacher , Nicolas Derval , et al Added: 3 years ago
Atrial fibrillation (AF) is the most commonly encountered arrhythmia in clinical practice. The discovery that pulmonary veins (PV) play a prominent role in the pathogenesis of AF has revolutionised the management of AF. PV isolation has become the most widely used technique for treatment of paroxysmal AF. Since the initial discovery implicating PVs in AF pathogenesis, the mechanistic link between… View more
Author(s): Jonathan W Waks , Mark E Josephson Added: 3 years ago
Atrial fibrillation (AF), the most common sustained arrhythmia, is a leading cause of stroke, and is associated with significant morbidity and mortality worldwide. Despite its frequency, clinical importance, and advances in technology and our knowledge of the molecular, ionic and physiological fundamentals of cardiac electrophysiology, our limited understanding of the mechanisms that initiate and… View more