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Author(s): Tom Nelson , Pankaj Garg , Richard H Clayton , et al Added: 3 years ago
Ventricular tachycardia (VT) and VF occur mainly in people with impaired cardiac function and/or ischaemic heart disease, and account for the majority of sudden cardiac deaths worldwide.1 Treatment with anti-arrhythmic drugs such as amiodarone may be at best neutral in terms of mortality and carries significant long-term risks.2,3 While ICDs significantly improve survival for patients with… View more

Imaging & Diagnostics

Electrophysiology & Arrhythmia
Author(s): Philippe Charron , Eloisa Arbustini , Gisèle Bonne Added: 3 years ago
Most mutations of the LMNA gene affect the heart, causing a dilated cardiomyopathy, ususally with conduction defect and ventricular arrhythmia, with or without skeletal muscle involvement. Although a relatively rare disease, cardiologists should be aware of laminopathies (diseases caused by LMNA gene mutations) because of the particularly aggressive course compared with most other… View more

Heterogeneous Populations

Electrophysiology & Arrhythmia
Author(s): Ethan R Ellis , Mark E Josephson Added: 3 years ago
Cardiomyopathies are heterogeneous heart muscle disorders with a wide range of aetiologies and clinical manifestations. They are often defined by their causes (i.e. hypertension, prior myocardial infarction, valvular heart disease), although current major society definitions describe cardiomyopathy as the presence of abnormal myocardial structure and/or function in the absence of underlying… View more

Heart Failure

Electrophysiology & Arrhythmia
Author(s): Laurent Roten , Matthew Daly , Patrizio Pascale , et al Added: 3 years ago
With an ageing population and widespread use of implantable cardioverter-defibrillators, physicians are confronted with an increasing number of patients with symptomatic, drug-refractory ventricular tachycardia (VT). Catheter ablation is an important treatment option in the management of patients with structural heart disease and VT.1,2 In many patients, VT can be successfully ablated from the… View more

Electrophysiology & Arrhythmia
Carina Blomström-Lundqvist
Research Area(s) / Expertise: Job title: Professor of Cardiology
Dr Carina Blomström-Lundqvist is Professor of Cardiology at the Department of Cardiology, Institution of Medical Science, Uppsala, SE and Senior Consultant and Professor at the Department of Cardiology and Medical Science, Örebro University Hospital, Örebro, SE. Dr Blomström-Lundqvist graduated in medicine in 1976, she went on to specialise in cardiology and internal medicine, and started… View more
Author(s): Angelo Auricchio Added: 3 years ago
Despite the fact that more than 20 years have passed since the clinical introduction of cardiac resynchronisation therapy (CRT), one of the key questions – do we need an ICD for primary prevention of sudden cardiac death (SCD) in CRT patients? – is still unanswered. Prospective Randomised Controlled Trials Multiple prospective randomised controlled trials have been conducted to establish the… View more

Electrophysiology & Arrhythmia
Primer on Machine Learning in Electrophysiology
Author(s): Shane E Loeffler , Natalia A Trayanova Added: 1 year ago

Imaging & Diagnostics

Electrophysiology & Arrhythmia
Sanjay Prasad
Job title: Consultant in cardiology and cardiovascular magnetic resonance Professor of cardiomyopathy
Dr. Sanjay Prasad ran the Virgin London Marathon in 2016 to raise money for the Alexander Jansons Foundation, an organisation which was set up to fund research conducted by the Royal Brompton Hospital into causes, prevention and cures for Myocarditis.¹ He is also a musician and used to play in a jazz band. Academic History Dr. Prasad studied for his medical degree at the University of Wales in… View more
Multimodality Imaging to Guide Ventricular Tachycardia Ablation in Patients with Non-ischaemic Cardiomyopathy
Author(s): Ling Kuo , Jackson J Liang , Saman Nazarian , et al Added: 3 years ago
Catheter ablation has been increasingly used as a treatment for refractory ventricular tachycardia (VT) in patients with non-ischaemic cardiomyopathy (NICM). However, ablation outcomes tend to be quite variable because of the heterogeneity of the aetiology for the NICM and associated VT substrate in these patients.1–3 Patients with NICM can be sub-classified based on specific genotypic and… View more

Imaging & Diagnostics

Electrophysiology & Arrhythmia
Author(s): Joshua R Silverstein , Demosthenes G Katritsis , Mark E Josephson Added: 3 years ago
Sudden cardiac death (SCD) is one of the leading causes of death in developed countries. The yearly incidence of SCD is estimated to be 3,000,000 worldwide and between 300,000–450,000 in both the US and Western Europe.1,2 The survival rate for SCD is <1 % worldwide and close to 5 % in the developed world.3 In the past, cardiac arrest was thought to be most commonly due to ventricular… View more

Electrophysiology & Arrhythmia