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Rhythm Control in Heart Failure Patients with Atrial Fibrillation
Author(s): William Eysenck , Magdi Saba Added: 3 years ago
Sir James Mackenzie, famous for describing the first mechanistic insights into AF in 1902 using his polygraph, also reported that AF was present in 80–90% of patients who had congestive heart failure (HF) in 1920.1 Today, the conditions are the two ‘epidemics’ of cardiovascular disease.2 They are dominating cardiovascular care and, with increasing longevity, they will become more prevalent and… View more

Heart Failure

Electrophysiology & Arrhythmia
Author(s): Satoshi Higa , Li-Wei Lo , Shih-Ann Chen Added: 3 years ago
Catheter ablation of AF has become an established therapy and may have the potential to cure this most commonly encountered sustained arrhythmia. Previous studies have demonstrated that pulmonary veins (PVs) are a major source of the ectopic beats that initiate AF. PV isolation in patients with symptomatic paroxysmal AF refractory to antiarrhythmic drugs is effective; however, it is difficult to… View more

Electrophysiology & Arrhythmia
His–Purkinje Conduction System Pacing: State of the Art in 2020
Author(s): Ahran D Arnold , Zachary I Whinnett , Pugazhendhi Vijayaraman Added: 3 years ago
Right ventricular apical pacing (RVAP) results in dyssynchronous ventricular activation that can lead to impairment of ventricular function. Alternative myocardial pacing sites such as RV septal pacing (RVSP) and RV outflow tract pacing still rely on myocardial cell-to-cell conduction and have not been shown to prevent pacing-induced cardiomyopathy.1 Biventricular pacing (BVP) certainly improves… View more

Electrophysiology & Arrhythmia
Ventricular Arrhythmia after Acute MI
Author(s): Justine Bhar-Amato , William Davies , Sharad Agarwal Added: 3 years ago
Ventricular tachyarrhythmias (VAs) most commonly occur early in ischaemia, and patients presenting with an acute MI and ventricular arrhythmias are a group that has a significantly increased risk of mortality.1,2 Thrombolysis primary percutaneous coronary intervention (PCI) and use of beta-blockers, while resulting in the modification of the natural history of an infarct, have also reduced the… View more

Electrophysiology & Arrhythmia

MI/ACS
Author(s): Tom Nelson , Pankaj Garg , Richard H Clayton , et al Added: 3 years ago
Ventricular tachycardia (VT) and VF occur mainly in people with impaired cardiac function and/or ischaemic heart disease, and account for the majority of sudden cardiac deaths worldwide.1 Treatment with anti-arrhythmic drugs such as amiodarone may be at best neutral in terms of mortality and carries significant long-term risks.2,3 While ICDs significantly improve survival for patients with… View more

Imaging & Diagnostics

Electrophysiology & Arrhythmia
Neuromodulation for Atrial Fibrillation
Author(s): Tolga Aksu , Jamario R Skeete , Henry H Huang Added: 1 year ago

Electrophysiology & Arrhythmia
Arrhythmias and Conduction Disturbances in Autoimmune Rheumatic Disorders
Author(s): Sotiris C Plastiras , Haralampos M Moutsopoulos Added: 3 years ago

Electrophysiology & Arrhythmia
Author(s): Geoffrey F Lewis , Michael R Gold Added: 3 years ago
Since the introduction of CRT more than 20 years ago, its role in mild to severe systolic heart failure has become well established. CRT has been shown to decrease mortality, reduce heart failure hospitalisations and improve functional status in patients with NYHA class II–IV heart failure and QRS prolongation, most commonly with LBBB pattern.1 One of the major limitations of CRT implementation… View more

Heart Failure

Electrophysiology & Arrhythmia
Author(s): Konstantinos N Aronis , Rheeda L Ali , Jialiu A Liang , et al Added: 3 years ago
The pathophysiology of AF is complex and incompletely understood to date.1,2 AF is a progressive disease of the atria involving a multitude of mechanisms related to its initiation, maintenance and progression. Experimental evidence suggest that AF is characterised by alternations in atrial size, shape electrophysiology, autonomic innervation, and cardiomyocyte metabolism, as well as development… View more

Electrophysiology & Arrhythmia
Author(s): Adryan A Perez , Frank W Woo , Darren C Tsang , et al Added: 3 years ago
The use of cardiovascular implantable electronic devices (CIEDs) has increased dramatically, with approximately 1.2–­1.4 million CIEDs implanted annually worldwide.1 In the US alone, there are more patients with CIEDs than registered nurses.2,3 CIEDs use leads that connect a generator to cardiac tissue to treat patients with many conditions including symptomatic bradycardia, morbid tachycardia… View more

Electrophysiology & Arrhythmia