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Author(s): Katrina Mountfort , Reinoud Knops , Johannes Sperzel , et al Added: 3 years ago
Based on Presentations at Nanostim Sponsored Symposium Held at the European Society of Cardiology Congress 2013, Amsterdam, The Netherlands, 2 September 2013 In 1958, the world’s first patient was implanted with a pacemaker. It brought numerous benefits, the most important of which was increased survival. Since then, pacemaker technology has evolved with the development of improved device… View more

Vascular Disease and Surgery

Electrophysiology & Arrhythmia
Author(s): Antonio Sorgente , Riccardo Cappato Added: 3 years ago
Cardiac resynchronisation therapy (CRT) is a well-established non-pharmacological treatment option for patients with refractory symptomatic heart failure (HF) already under optimal medical therapy.1 CRT is founded on the principle that interventricular conduction disturbances and especially left bundle branch block (LBBB) are deleterious to cardiac performance and may contribute to the systolic… View more

Heart Failure

Electrophysiology & Arrhythmia
Early Repolarisation – What Should the Clinician Do?
Author(s): Manoj N Obeyesekere , Andrew D Krahn Added: 3 years ago
Early repolarisation (ER) is defined as J-point elevation of ≥0.1 mV in two adjacent leads with either a slurred or notched morphology (Figures 1 to 4).1,2 Numerous studies have established an association with ER and increased risk of death and idiopathic ventricular fibrillation (VF).1–5 Clinicians face questions such as patient and family counselling, quantitifying the risk of sudden cardiac… View more

Electrophysiology & Arrhythmia
Author(s): Sanjiv M Narayan , David E Krummen Added: 3 years ago
Atrial fibrillation (AF) is the most prevalent arrhythmia in the world and a leading cause of hospitalisation and death.1 Current therapy for AF remains suboptimal, in large part because its mechanisms are uncertain. However, recent advances in our understanding of human AF, from meticulous mapping in patients and insights from animal models, are providing new therapeutic options for patients. … View more

Electrophysiology & Arrhythmia
Author(s): Jens Kienemund , Karl-Heinz Kuck , Christian Frerker Added: 3 years ago
Prevalence of Functional Mitral Regurgitation in Patients with Chronic Heart Failure Secondary or functional mitral regurgitation (FMR) is a common problem in patients with chronic heart failure (HF) due to dilated cardiomyopathy, regardless of aetiology.1 FMR results from an imbalance between the closing and the tethering forces that act on the mitral valve leaflets.2,3 A chart review of… View more

Heart Failure

Electrophysiology & Arrhythmia
Author(s): Tom Nelson , Pankaj Garg , Richard H Clayton , et al Added: 3 years ago
Ventricular tachycardia (VT) and VF occur mainly in people with impaired cardiac function and/or ischaemic heart disease, and account for the majority of sudden cardiac deaths worldwide.1 Treatment with anti-arrhythmic drugs such as amiodarone may be at best neutral in terms of mortality and carries significant long-term risks.2,3 While ICDs significantly improve survival for patients with… View more

Imaging & Diagnostics

Electrophysiology & Arrhythmia
Author(s): Josef Kautzner , Petr Peichl Added: 3 years ago
Ventricular fibrillation (VF) is a complex arrhythmia that leads invariably to cardiac arrest. Its mechanisms remain largely unclear. Similar to atrial fibrillation, the mother rotor hypothesis is one plausible alternative.1,2 In larger animals, some authors reported that the dominant frequency of VF could be recorded at a junction of the left ventricular posterior wall and the septum.3-6 Others… View more

Electrophysiology & Arrhythmia

MI/ACS
ECGI Mapping of Ventricular Tachycardia
Author(s): Adam J Graham , Richard Schilling Added: 2 years ago

Imaging & Diagnostics

Electrophysiology & Arrhythmia
Leadless LV Endocardial Pacing and LBBAP
Author(s): Baldeep S Sidhu , Justin Gould , Mark Elliott , et al Added: 3 years ago

Electrophysiology & Arrhythmia
Author(s): Hussam Ali , Pierpaolo Lupo , Riccardo Cappato Added: 3 years ago
Numerous large clinical trials have demonstrated the benefit of implantable cardioverter-defibrillators (ICDs) to prevent sudden cardiac death (SCD) in selected populations.1,2 These results and advances in defibrillation therapies have led to an impressive expansion of ICD implants and indications in recent decades. Although initially focusing on secondary prevention, current ICD indications… View more

Heart Failure

Electrophysiology & Arrhythmia