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Author(s): George Thomas , Jiwon Kim , Bruce B Lerman Added: 3 years ago
CRT is an essential treatment for patients with heart failure and reduced ejection fraction as it can restore left ventricular (LV) electrical and mechanical synchrony. It has been shown to increase quality of life, improve functional status, reduce hospitalisation, improve LV systolic function and reduce mortality in properly selected patients.1,2 While CRT is an effective therapy, approximately… View more
Author(s): Geoffrey F Lewis , Michael R Gold Added: 3 years ago
Since the introduction of CRT more than 20 years ago, its role in mild to severe systolic heart failure has become well established. CRT has been shown to decrease mortality, reduce heart failure hospitalisations and improve functional status in patients with NYHA class II–IV heart failure and QRS prolongation, most commonly with LBBB pattern.1 One of the major limitations of CRT implementation… View more
Author(s): Nishant Verma , Bradley P Knight Added: 3 years ago
A Brief History of Cardiac Pacing Electrical stimulation of the heart was used sporadically throughout the 19th century, generating a set of case reports, largely related to attempts to resuscitate people.1 The contemporary field of cardiac pacing emerged in the 20th century (Figure 1). The first use of pacemakers in a modern sense was in the late 1920s when Australian anaesthetist Mark Lidwell… View more
Author(s): Demosthenes G Katritsis , Andrew Grace , Angelo Auricchio , et al Added: 3 years ago
The most important papers on arrhythmias and electrophysiology published in 2017, selected by the editors of Arrhythmia and Electrophysiology Review (AER). CLINICAL PRACTICE Ortiz M, Martín A, Arribas F, et al. Randomized comparison of intravenous procainamide vs. intravenous amiodarone for the acute treatment of tolerated wide QRS tachycardia: the PROCAMIO study. Eur Heart J 2017;38:1329–35… View more
Author(s): Henry Chubb , Mark O’Neill , Eric Rosenthal Added: 3 years ago
Device therapy is increasingly employed in the management of complex congenital heart disease (CHD). Bradycardias, most often related to sinus nodal dysfunction (SND) or atrioventricular nodal (AVN) block, may necessitate the implantation of pacing devices, while malignant arrhythmias may be treated by appropriate use of implantable cardioverter defibrillators (ICDs). However, there is a complex… View more
Author(s): Francis E Marchlinski Added: 3 years ago
Catheter-based Mapping to Characterise Ventricular Tachycardia Catheter-based mapping of the left ventricle (LV) to characterise the substrate and origin of ventricular tachycardia (VT) was thought to involve a much greater level of risk and therefore not to be pursued. Mark proved the naysayers wrong with his careful and methodical approach to evaluating the LV endocardium. What made these… View more
Author(s): John M Miller Added: 3 years ago
The Electrocardiogram In the entire realm of his work, Dr Josephson’s greatest love was the simple electrocardiogram (ECG). His discernment, based on the ECG, into the patient’s history and disease processes was legendary. Among the more important and insightful contributions he made to our understanding of heart disease and arrhythmias from the ECG are: observations of alternating preexcitation… View more