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Author(s): Konstantinos C Siontis , Hakan Oral Added: 3 years ago
Advanced catheter-based technologies employed for the ablation of symptomatic atrial fibrillation (AF) have revolutionised the management of this common sustained arrhythmia. In the late 1990s, premature depolarisations originating from the myocardial sleeves within the pulmonary veins were recognised to initiate AF. This landmark discovery rendered pulmonary vein isolation (PVI) as the… View more
Author(s): Giuseppe Mascia , Marzia Giaccardi Added: 3 years ago
X-rays used in interventional cardiology are proven (class I) carcinogens, and the electrophysiology community should make every effort to give “the right imaging exam, with the right dose, to the right patient”.1 This may be an effective strategy for the primary prevention of cancer for physicians, medical staff and patients (particularly children, young adults and women).2 The impact of X-rays… View more
Author(s): Ruairidh Martin , Meleze Hocini , Michel Haissaguerre , et al Added: 3 years ago
Ventricular tachycardia (VT) in the context of structural heart disease is related to patchy or incomplete scar; usually arising from re-entrant circuits which are dependent on surviving channels of activation through scar tissue.1–3 These protected isthmuses are critical for maintaining VT, and an improved understanding of the characteristics of VT isthmuses is important in guiding strategies… View more
Author(s): Caroline H Roney , Andrew L Wit , Nicholas S Peters Added: 3 years ago
Determining optimal treatment strategies for complex arrhythmogenesis in AF is confounded by the lack of consensus on the mechanisms causing AF. Fundamental to defining arrhythmogenic mechanisms of AF are the distinctions and interplay between functional features (determined by the electrophysiology of a cell) and structural features (determined by whether a structural or anatomical feature is… View more
Author(s): Henry Chubb , Mark O’Neill , Eric Rosenthal Added: 3 years ago
Device therapy is increasingly employed in the management of complex congenital heart disease (CHD). Bradycardias, most often related to sinus nodal dysfunction (SND) or atrioventricular nodal (AVN) block, may necessitate the implantation of pacing devices, while malignant arrhythmias may be treated by appropriate use of implantable cardioverter defibrillators (ICDs). However, there is a complex… View more
Author(s): Zhao Liu , J Kevin Donahue Added: 3 years ago
In the United States, atrial fibrillation (AF) is the most common sustained cardiac arrhythmia affecting approximately six million patients and contributing to a greatly increased risk of stroke, heart failure (HF) and overall morbidity and mortality.1,2 The prevalence of AF is increasing as the average age of the population increases.3,4 Currently available therapies for AF are suboptimal… View more
Author(s): Marius Andronache , Nikola Drca , Graziana Viola Added: 3 years ago
AF is the most common sustained cardiac arrhythmia in clinical practice. It is associated with increased risk of stroke and heart failure (HF), and is a significant global health challenge.1 Catheter ablation procedures, which isolate the pulmonary veins (PV) from the left atrium and prevent AF initiation, are effective and safe treatment options, and have emerged as the preferred rhythm control… View more