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HRS 2026 – Dr Enrico Ferro (Beth Israel Deaconess Medical Center, Boston, MA) returns to discuss findings from a large single-centre comparative safety analysis of pulsed field ablation (PFA) versus radiofrequency (RF) ablation for atrial fibrillation, originally presented at EHRA 2026 in Paris as a Young Investigator Award submission.Conducted at one of the highest-volume PVI centres in the US,…
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1 month ago
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Arrhythmia Academy
A substudy of the ADVANTAGE AF trial has demonstrated that for treating typical atrial flutter (AFL), pulsed field ablation (PFA) is as effective and safe as conventional radiofrequency ablation (RFA), but significantly more efficient.¹ The study focused on adjunctive cavotricuspid isthmus (CTI) ablation, a common procedure performed during atrial fibrillation (AF) ablation.Mechanism of ActionPFA…
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2 weeks ago
HRS Congress 2026 – Dr Christopher Porterfield (Aurora Denver Cardiology, Aurora, CO, US) discusses findings from the REAL-AF Registry, examining the safety and effectiveness of variable loop circular catheter pulsed field ablation across a broad range of patient and procedural characteristics in real-world clinical settings.The REAL-AF Registry is a prospective, multicentre, observational study…
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3 weeks ago
EHRA 2026 — Dr David Schaack (CCB am Markus Hospital, Frankfurt am Main, Germany) joins us to discuss findings from the ULYSSES trial, evaluating whether ultrasound-guided venous puncture reduces access site complications in patients undergoing atrial fibrillation ablation.This investigator-initiated, prospective, randomised multicentre trial enrolled 1,075 patients with AF or left atrial…
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Complications of Pulsed Field Ablation for AF
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3 weeks ago
Review Article
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1 month ago
EHRA Congress 2026 – Prof Roland Tilz (University Hospital Schleswig-Holstein, Lübeck, DE) presents the findings from the TiFFANY-AF study, a retrospective observational analysis evaluating real-world mortality outcomes associated with pulsed field ablation compared with thermal ablation techniques — radiofrequency and cryoballoon — for atrial fibrillation.Drawing on a decade of data from the US…
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1 month ago
Dr Melanie Gunawardene joins us to examine whether integrated mapping and ablation technology is ready to redefine how we approach atrial fibrillation ablation in the modern EP lab.The Sphere-9 catheter and Affera mapping system represent a significant step toward consolidating what has traditionally required multiple tools into a single-catheter workflow — combining high-density mapping with PFA…
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EHRA 2026 – Dr Stylianos Tzeis (Mitera Hospital, Athens, GR) joins us to discuss findings from the LINEAR study, a prospective, multicentre randomised trial comparing lattice-tip and irrigated-tip catheter technologies for radiofrequency ablation of the cavotricuspid isthmus (CTI).This randomised controlled trial enrolled 96 patients undergoing CTI ablation across multiple centres, randomised 1:1…
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