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Challenges Associated with Interpreting Mechanisms of AF
Author(s): Caroline H Roney , Andrew L Wit , Nicholas S Peters Added: 3 years ago
Determining optimal treatment strategies for complex arrhythmogenesis in AF is confounded by the lack of consensus on the mechanisms causing AF. Fundamental to defining arrhythmogenic mechanisms of AF are the distinctions and interplay between functional features (determined by the electrophysiology of a cell) and structural features (determined by whether a structural or anatomical feature is… View more

Electrophysiology & Arrhythmia
Anisotropic Cardiac Conduction
Author(s): Irum D Kotadia , John Whitaker , Caroline H Roney , et al Added: 3 years ago

Electrophysiology & Arrhythmia
Author(s): Ian Mann , Belinda Sandler , Nick WF Linton , et al Added: 3 years ago
The discovery of focal ectopy in the pulmonary veins (PVs) initiating AF1 has resulted in electrical isolation of the PVs forming the mainstay of current treatment strategies. Success rates from PV isolation (PVI) for patients with paroxysmal AF (PAF) are approximately 70–75%. However, PVI is significantly less effective for those with persistent AF, in whom many studies quote single-procedure… View more

Electrophysiology & Arrhythmia
Electrophysiologist in Convergent Ablation
Author(s): Nadeev Wijesuriya , Nikos Papageorgiou , Edd Maclean , et al Added: 3 years ago
AF is the most common arrhythmia and about 10% of the general population above the age of 65 years are affected by this condition.1 The mortality and morbidity of AF is well established, with a higher risk of stroke and heart failure in older patients with comorbidities.2 The pathophysiology of AF is complex and variable, making its management extremely challenging. Epidemiological studies have… View more

Electrophysiology & Arrhythmia
Atrial Flutter, Typical and Atypical: A Review
Author(s): Francisco G Cosio Added: 3 years ago
The term ‘flutter’ was coined to designate the visual and tactile rapid, regular atrial contraction induced by faradic stimulation in animal hearts, in contrast with irregular, vermiform contraction in atrial fibrillation (AF).1,2 On the ECG, flutter was a regular continuous undulation between QRS complexes at a cycle length (CL) of ≤250 ms (≥240 bpm). Slower tachycardias displaying discrete P… View more

Electrophysiology & Arrhythmia
Dynamic High-Density Functional Substrate Mapping In Ventricular Tachycardia Ablation
Author(s): Neil T Srinivasan Added: 3 years ago
Dr Neil Srinivasan (Essex Cardiothoracic Centre, Basildon, UK) evaluates of the role of dynamic substrate changes in facilitating conduction delay and re-entry in ventricular tachycardia (VT) circuits. Recorded remotely from Basildon, 2020. View more

Electrophysiology & Arrhythmia
DeEP Mapping: Elucidating the Functional VT Substrate
Author(s): Abhishek Bhaskaran , John Fitzgerald , Nicholas Jackson , et al Added: 3 years ago

Electrophysiology & Arrhythmia
Limitations in Mapping Ventricular Tachycardia
Author(s): Adam J Graham , Michele Orini , Pier D Lambiase Added: 3 years ago
Recurrent episodes of ventricular tachycardia (VT) in patients with structural heart disease are associated with increased mortality and morbidity, despite the life-saving benefits of implantable cardiac defibrillators (ICDs).1,2 Because ICD therapies are abortive and do not alter the underlying arrhythmogenic substrate, their reduction becomes important, especially as recurrent shocks can cause… View more

Electrophysiology & Arrhythmia
Author(s): Saagar Mahida , Frédéric Sacher , Nicolas Derval , et al Added: 3 years ago
Atrial fibrillation (AF) is the most commonly encountered arrhythmia in clinical practice. The discovery that pulmonary veins (PV) play a prominent role in the pathogenesis of AF has revolutionised the management of AF. PV isolation has become the most widely used technique for treatment of paroxysmal AF. Since the initial discovery implicating PVs in AF pathogenesis, the mechanistic link between… View more

Electrophysiology & Arrhythmia
Author(s): Eyal Nof , William G Stevenson , Roy John Added: 3 years ago
Sustained ventricular tachycardia (VT) and ventricular fibrillation (VF) are typically a manifestation of significant structural heart disease and often associated with a high risk of sudden cardiac death. Implantable cardioverter defibrillators (ICDs) remain the mainstay of therapy for prevention of sudden cardiac death associated with these arrhythmias.1 However, ICDs treat the arrhythmia after… View more

Electrophysiology & Arrhythmia