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Author(s):
Jens Kienemund
,
Karl-Heinz Kuck
,
Christian Frerker
Added:
3 years ago
Prevalence of Functional Mitral Regurgitation in Patients with Chronic Heart Failure
Secondary or functional mitral regurgitation (FMR) is a common problem in patients with chronic heart failure (HF) due to dilated cardiomyopathy, regardless of aetiology.1 FMR results from an imbalance between the closing and the tethering forces that act on the mitral valve leaflets.2,3
A chart review of…
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Author(s):
Penelope A Boyden
,
Wen Dun
,
Bruno D Stuyvers
Added:
3 years ago
Abnormalities in electrical rhythm were studied by Einthoven at the start of the 20th century. In the 1940s, studies by Bozler et al.1 described contractile signals that appeared to be ‘triggered’ heart beats. Today we use the term delayed afterdepolarisations (DADs) to refer to oscillations in voltage that follow a driven action potential.
In the mid-1970s, progress was made when Lederer and…
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Author(s):
Ghanshyam Shantha
,
Frank Pelosi
,
Fred Morady
Added:
3 years ago
Prevalence of AF and Obstructive Sleep Apnoea
Nonvalvular AF is the most common sustained arrhythmia, affecting nearly 3 million adult Americans.1–4 By 2050, nearly 12–15 million adults in the US will have AF.1 The global prevalence of obstructive sleep apnoea (OSA) is also increasing. OSA is the most common form of sleep-disordered breathing, affecting 10–15% of the general population (6–9% in…
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A Critical Reappraisal of the Current Clinical Indications to Cardiac Resynchronisation Therapy
Author(s):
Antonio Sorgente
,
Riccardo Cappato
Added:
3 years ago
Article
Author(s):
Niek EG Beurskens
,
Fleur VY Tjong
,
Reinoud Knops
Added:
3 years ago
Since its introduction in 2012, leadless pacemaker (LP) therapy has developed as a therapeutic alternative to conventional transvenous pacemaker (PM) therapy to circumvent lead- and pocket-related complications.1-4 To date, two LPs are available for patients with a single-chamber pacing (VVI) indication: the Nanostim Leadless Cardiac Pacemaker (LCP; Abbott) and the Micra Transcatheter Pacing…
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Author(s):
Jonathan W Waks
,
Mark E Josephson
Added:
3 years ago
Atrial fibrillation (AF), the most common sustained arrhythmia, is a leading cause of stroke, and is associated with significant morbidity and mortality worldwide. Despite its frequency, clinical importance, and advances in technology and our knowledge of the molecular, ionic and physiological fundamentals of cardiac electrophysiology, our limited understanding of the mechanisms that initiate and…
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Author(s):
Jonathan S Steinberg
,
David Slotwiner
Added:
3 years ago
Electrical Remodelling
Evidence Supporting Atrial Remodelling
The concept of electrical remodelling was first introduced in 1995 simultaneously by Wijffels et al.1 and Morillo et al.2 who demonstrated that once sustained atrial fibrillation (AF) was induced in goats, or rapid atrial pacing was performed in dogs, physiological changes occurred that favoured the maintenance of AF.3 This led to the…
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Author(s):
Federico Lombardi
Added:
3 years ago
Atrial fibrillation (AF) is the most common clinical arrhythmia with a relevant socio-economic impact.1–3 Patients with atrial fibrillation are characterised by symptoms such as palpitations and shortness of breath; they have reduced exercise capacity and are subject to a higher risk of thromboembolic events. In spite of a relatively simple diagnosis, management of AF patients is difficult for…
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Atrial Myopathy Underlying AF
Author(s):
Harold Rivner
,
Raul D Mitrani
,
Jeffrey J Goldberger
Added:
3 years ago
Article
Author(s):
Lluis Mont
,
Ivo Roca-Luque
,
Till F Althoff
Added:
1 year ago