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Author(s): Geoffrey F Lewis , Michael R Gold Added: 3 years ago
Since the introduction of CRT more than 20 years ago, its role in mild to severe systolic heart failure has become well established. CRT has been shown to decrease mortality, reduce heart failure hospitalisations and improve functional status in patients with NYHA class II–IV heart failure and QRS prolongation, most commonly with LBBB pattern.1 One of the major limitations of CRT implementation… View more
Author(s): Sanjiv M Narayan , David E Krummen Added: 3 years ago
Atrial fibrillation (AF) is the most prevalent arrhythmia in the world and a leading cause of hospitalisation and death.1 Current therapy for AF remains suboptimal, in large part because its mechanisms are uncertain. However, recent advances in our understanding of human AF, from meticulous mapping in patients and insights from animal models, are providing new therapeutic options for patients. … View more
Author(s): Ngai-Yin Chan Added: 3 years ago
Atrial fibrillation (AF) is the most common sustained heart rhythm disorder1 and in a recently conducted community screening programme in Hong Kong the total burden of AF in the population was estimated to be 0.77% in 2016. This is predicted to increase to 1.1% in 2030 due to population ageing, see Figure 1.2 As in other developed countries and regions with ageing populations, AF has become an… View more
Author(s): Satish Raj , Robert Sheldon Added: 3 years ago
Syncope and palpitations are two common clinical presentations, and both pose difficulties in the approach to their management. They are both symptoms of a number of syndromes, and an efficient approach with targeted therapy is challenging. Cardiac arrhythmia specialists, who lack a compact and accessible guide to management, see many patients with these symptoms in consultation. Recognising this… View more
Author(s): Axel Brandes , Marcelle D Smit , Bao Oanh Nguyen , et al Added: 3 years ago
Atrial fibrillation (AF) is the most common clinical arrhythmia worldwide and is expected to increase in the coming decades.1,2 It currently affects up to 3 % of Western populations aged 20 years or older, and the number of affected individuals in the EU will increase from about 7 million to almost 13 million by 2030.3–5 This growing epidemic is not only caused by the natural ageing of the… View more
Author(s): Rakesh Gopinathannair , Benjamin C Salgado , Brian Olshansky Added: 3 years ago
Heart rate and blood pressure are tightly regulated by autonomic control to effect adequate blood flow as needed. This regulatory process breaks down when the vasovagal reflex is activated. Profound, but brief, circulatory collapse manifests as bradycardia (cardioinhibitory response) and/or hypotension (vasodepressor response) and/or altered cerebral autoregulation, resulting in transient loss of… View more