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Author(s): Jonathan W Waks , Mark E Josephson Added: 3 years ago
Atrial fibrillation (AF), the most common sustained arrhythmia, is a leading cause of stroke, and is associated with significant morbidity and mortality worldwide. Despite its frequency, clinical importance, and advances in technology and our knowledge of the molecular, ionic and physiological fundamentals of cardiac electrophysiology, our limited understanding of the mechanisms that initiate and… View more
Dr David Calvo Cuervo is a Consultant in Cardiology, Invasive and Clinical Cardiac Electrophysiology at the University Central Hospital of Asturias, Spain. He has trained at the Central University Hospital of Asturias, Universidad Complutense Madrid, and Central University Hospital Gregorio Marañón in Spain. In 2007 he completed a Research Fellowship in Experimental Cardiac Electrophysiology at… View more
Dr David Calvo Cuervo is a Consultant in Cardiology, Invasive and Clinical Cardiac Electrophysiology at the University Central Hospital of Asturias, Spain. He has trained at the Central University Hospital of Asturias, Universidad Complutense Madrid, and Central University Hospital Gregorio Marañón in Spain. In 2007 he completed a Research Fellowship in Experimental Cardiac Electrophysiology… View more
Author(s): Michael Ghannam , Hakan Oral Added: 3 years ago
Maintenance of sinus rhythm in patients with non-paroxysmal AF is often challenging and complex. Catheter ablation is usually superior to anti-arrhythmic drug therapy alone. However, recurrence rates are high and have remained suboptimal. Although pulmonary vein isolation (PVI) is usually effective in treating paroxysmal AF, it is not sufficient for many patients with non-paroxysmal AF,… View more
Research Area(s) / Expertise:

Atrial Fibrillation

Job title: Assistant Professor of Clinical Medicine
Junaid AB Zaman, MA, BMBCh, MRCP, PhD, is a Clinical Assistant Professor of Medicine in the Division of Cardiology at University of Southern California. He also holds honorary appointments as a Consultant Cardiologist and Electrophysiologist at the Royal Brompton Hospital, London and as a Senior Clinical Lecturer at Imperial College London. Since graduation from the University of Oxford, he has… View more
Research Area(s) / Expertise: Job title: MB, BCHIR
Prapa Kanagaratnam is a Consultant Cardiologist at St Mary’s Hospital, Imperial College Healthcare in London. His clinical and research interests are the ablation of cardiac arrhythmias and device therapy. His research is supported by the National Institute for Health Research (NIHR) Biomedical Research Centre Funding Scheme and the British Heart Foundation. In 2001, he was the recipient of the… View more
Author(s): Amir S Jadidi , Thomas Arentz Added: 3 years ago
Adecade after its first description as ‘the electrophysiological substrate’ of atrial fibrillation,1 mapping complex fractionated atrial electrogram (CFAE) as an ablation target for atrial fibrillation (AF) remains highly controversial. Early high-density mapping studies of induced AF in humans revealed distinct mechanisms that underlie electrogram fractionation: collision areas of distinct… View more
Author(s): Konstantinos C Siontis , Hakan Oral Added: 3 years ago
Advanced catheter-based technologies employed for the ablation of symptomatic atrial fibrillation (AF) have revolutionised the management of this common sustained arrhythmia. In the late 1990s, premature depolarisations originating from the myocardial sleeves within the pulmonary veins were recognised to initiate AF. This landmark discovery rendered pulmonary vein isolation (PVI) as the… View more