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Author(s):
Jonathan W Waks
,
Mark E Josephson
Added:
3 years ago
Atrial fibrillation (AF), the most common sustained arrhythmia, is a leading cause of stroke, and is associated with significant morbidity and mortality worldwide. Despite its frequency, clinical importance, and advances in technology and our knowledge of the molecular, ionic and physiological fundamentals of cardiac electrophysiology, our limited understanding of the mechanisms that initiate and…
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David Calvo Cuervo
Author
David Calvo
Author
Author(s):
Junaid Zaman
,
Andrew Grace
,
Sanjiv M Narayan
Added:
1 year ago
Author(s):
Michael Ghannam
,
Hakan Oral
Added:
3 years ago
Maintenance of sinus rhythm in patients with non-paroxysmal AF is often challenging and complex. Catheter ablation is usually superior to anti-arrhythmic drug therapy alone. However, recurrence rates are high and have remained suboptimal. Although pulmonary vein isolation (PVI) is usually effective in treating paroxysmal AF, it is not sufficient for many patients with non-paroxysmal AF,…
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Junaid Zaman
Research Area(s) / Expertise:
Job title: Assistant Professor of Clinical Medicine
Author
Prapa Kanagaratnam
Research Area(s) / Expertise:
Job title: MB, BCHIR
Author
Author(s):
Amir S Jadidi
,
Thomas Arentz
Added:
3 years ago
Adecade after its first description as ‘the electrophysiological substrate’ of atrial fibrillation,1 mapping complex fractionated atrial electrogram (CFAE) as an ablation target for atrial fibrillation (AF) remains highly controversial. Early high-density mapping studies of induced AF in humans revealed distinct mechanisms that underlie electrogram fractionation: collision areas of distinct…
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Author(s):
Konstantinos C Siontis
,
Hakan Oral
Added:
3 years ago
Advanced catheter-based technologies employed for the ablation of symptomatic atrial fibrillation (AF) have revolutionised the management of this common sustained arrhythmia. In the late 1990s, premature depolarisations originating from the myocardial sleeves within the pulmonary veins were recognised to initiate AF. This landmark discovery rendered pulmonary vein isolation (PVI) as the…
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Author(s):
Phillip Cuculich
,
Pier D Lambiase
,
David Calvo Cuervo
Start date:
Jan 09, 2019
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