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Author(s):
Raphael K Sung
,
Penelope A Boyden
,
Satoshi Higuchi
,
et al
Added:
2 years ago
Author(s):
Eyal Nof
,
William G Stevenson
,
Roy John
Added:
3 years ago
Sustained ventricular tachycardia (VT) and ventricular fibrillation (VF) are typically a manifestation of significant structural heart disease and often associated with a high risk of sudden cardiac death. Implantable cardioverter defibrillators (ICDs) remain the mainstay of therapy for prevention of sudden cardiac death associated with these arrhythmias.1 However, ICDs treat the arrhythmia after…
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Author(s):
Jonathan W Waks
,
Mark E Josephson
Added:
3 years ago
Atrial fibrillation (AF), the most common sustained arrhythmia, is a leading cause of stroke, and is associated with significant morbidity and mortality worldwide. Despite its frequency, clinical importance, and advances in technology and our knowledge of the molecular, ionic and physiological fundamentals of cardiac electrophysiology, our limited understanding of the mechanisms that initiate and…
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Author(s):
Steven M Markowitz
,
George Thomas
,
Christopher F Liu
,
et al
Added:
3 years ago
Pioneering electrophysiology studies in the 1990s defined the anatomical boundaries of typical atrial flutter, identified regions for effective catheter ablation of this arrhythmia and described procedural endpoints to minimise recurrences after ablation. Activation and entrainment mapping demonstrated that typical flutter arises from reentry around the tricuspid annulus.1 Criteria to confirm…
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Author(s):
John M Miller
Added:
3 years ago
The Electrocardiogram
In the entire realm of his work, Dr Josephson’s greatest love was the simple electrocardiogram (ECG). His discernment, based on the ECG, into the patient’s history and disease processes was legendary. Among the more important and insightful contributions he made to our understanding of heart disease and arrhythmias from the ECG are: observations of alternating preexcitation…
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Author(s):
Sebastian Clauss
,
Moritz F Sinner
,
Stefan Kääb
,
et al
Added:
3 years ago
Atrial fibrillation (AF) is the most common arrhythmia experienced in clinical practice, and is responsible for significant morbidity and mortality.1 It affects more than 6 million people in Europe.1 The lifetime risk of developing AF after the age of 40 is approximately 25 %.1 AF is a major public health burden as it is associated with an increased risk of stroke by fivefold, dementia by twofold…
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Author(s):
Charlotte Brouwer
,
Mark G Hazekamp
,
Katja Zeppenfeld
Added:
3 years ago
The reported incidence of congenital heart disease (CHD) depends on the number of trivial lesions included, such as atrial and ventricular septal defects (ASDs and VSDs). Moderate-to-severe CHD numbers remain stable with 6 per 1,000 live births.1 Survival into adulthood has improved dramatically over the last 25 years and has been driven mainly by a decreased mortality in moderate and severe…
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Author(s):
Demosthenes G Katritsis
,
Mark E Josephson
Added:
3 years ago
Atrioventricular nodal reentrant tachycardia (AVNRT) denotes re-entry in the area of the AV node, and represents the most common regular arrhythmia in the human.1 Although several models have been proposed to explain the mechanism of the arrhythmia in the context of the complex anatomy and the anisotropic properties of the atrioventricular (AV) node and its atrial extensions (see Figure 1),2 the…
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Author(s):
Seigo Yamashita
,
Ashok J Shah
,
Saagar Mahida
,
et al
Added:
3 years ago
Catheter ablation therapy has been widely used for rhythm control in patients with atrial fibrillation(AF).1 Since the first report in 1994,2 several interventional techniques have been proposed for AF, including replication of the surgical Maze,2 targeting pulmonary vein (PV) foci,3 segmental ostial and circumferential PV isolation,4,5 ganglionated plexi ablation,6 linear lesions in the left…
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Author(s):
Nikolaos Papageorgiou
,
Neil T Srinivasan
Added:
2 years ago