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Author(s): Amar Trivedi , Bradley P Knight Added: 3 years ago
Hypertrophic cardiomyopathy (HCM), a genetic sarcomeric disorder associated with myocyte disarray and scar deposition, is intimately linked to sudden cardiac death (SCD) due to malignant ventricular arrhythmias. In the first modern published description of the disease in 1958, Dr Donald Teare describes the case of a 14-year-old male who collapsed while being chased around his school’s playground… View more
Author(s): Moinuddin Choudhury , Mark R Boyett , Gwilym M Morris Added: 3 years ago
The sinoatrial or sinus node (SAN) is the heart’s natural pacemaker. Located in the superior right atrium, it automatically produces cyclical electrical activity to initiate each heartbeat in normal sinus rhythm. SAN dysfunction (SND) in humans, also known as ‘sick sinus syndrome’, can manifest as pathological bradycardia and asystolic pauses. As a result, SND can lead to symptoms of reduced… View more
Author(s): Jorge E Romero , Dan L Li , Ricardo Avendano , et al Added: 3 years ago
Brugada syndrome (BrS), one of the most common causes of sudden cardiac death (SCD) in normal structural heart individuals, is a young entity in modern medicine. BrS was first characterised in 1992 by Brugada et al. as a distinct syndrome with “right bundle branch block, persistent ST elevation in precordial leads V1 to V2–3 and sudden cardiac death”.1 The true prevalence of BrS is not clearly… View more
Author(s): Luuk Heckman , Kevin Vernooy Added: 2 years ago
Luuk Heckman, from the Prof. Kevin Vernooy’s group at the Maastricht University Medical Center, provides Arrhythmia Academy with an overview on the performing AV node ablation and left bundle branch area pacemaker implantation in a single procedure. View more
Author(s): George D Katritsis , Vishal Luther , Prapa Kanagaratnam , et al Added: 3 years ago
The introduction of cardiac electroanatomic mapping systems in the mid-1990s has permitted investigators to record intracardiac electrograms (EGMs) with accurate spatial localisation in 3D.1 These 3D mapping systems have enabled the display of the cardiac chambers as an anatomical shell upon which voltage, or activation, information can be displayed. Most commonly, colour is used to represent the… View more
Author(s): Carina Blomström-Lundqvist , Tatjana S Potpara , Helena Malmborg Added: 3 years ago
With the advent of successful surgical repairs and modern diagnostic techniques, an increasing number of patients with congenital heart disease survive to adulthood. Despite these improvements, the surgical corrective atrial incisions performed during childhood lead to subsequent myocardial scarring that have the inherent risk of harbouring substrates for macro-reentrant atrial tachycardias … View more