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Author(s): Roderick Tung , Gaurav A Upadhyay Added: 3 years ago
In 1970, Durrer et al. recorded the total excitation of the human heart with 870 electrodes and confirmed the first 10 ms of left ventricular (LV) activation as trifascicular in nature.1 The rapid and synchronous activation of the LV through the specialised His–Purkinje network is highly intricate and efficient, preserving normal physiological coupling between electrical excitation and mechanical… View more
Author(s): Jens Kienemund , Karl-Heinz Kuck , Christian Frerker Added: 3 years ago
Prevalence of Functional Mitral Regurgitation in Patients with Chronic Heart Failure Secondary or functional mitral regurgitation (FMR) is a common problem in patients with chronic heart failure (HF) due to dilated cardiomyopathy, regardless of aetiology.1 FMR results from an imbalance between the closing and the tethering forces that act on the mitral valve leaflets.2,3 A chart review of… View more
Author(s): Bruce Wilkoff Added: 1 year ago
EHRA 23– Dr Bruce Wilkoff (Cleveland Clinic, US) joins us on-site to outline the findings of the AdaptResponse randomized study (NCT02205359). In AdaptResponse, investigators studied the hypothesis that cardiac resynchronization therapy (CRT) devices which utilised AdaptivCRT® (aCRT) algorithm (Medtronic) had better prognosis in patients with normal atrioventricular conduction and left bundle… View more
Author(s): Pugazhendhi Vijayaraman Added: 1 year ago
In this short interview from HRS 2022, Dr Pugazhendi Vijayaraman (Geisinger Heart Institute, Wilkes-Barre, Pennsylvania, US) outlines the findings from the CSP-SYNC trial which investigated the effects of conduction system pacing as compared to conventional biventricular pacing in patients with heart failure with preserved ejection fraction (HFpEF). Discussion Points: 1. Aim of this study 2… View more
Author(s): Jagmeet P Singh Added: 5 years ago
Professor Jagmeet Singh discusses ENHANCE CRT -Targeted left ventricular lead implantation in non-left bundle branch block patients. Filmed by Radcliffe Cardiology on-site at HRS 2018 in Boston, US. View more
Author(s): Nadine Ali , Daniel Keene , Ahran D Arnold , et al Added: 3 years ago
His bundle pacing in humans was first described in 1970 by Narula et al.1 They demonstrated that it was possible to stimulate the His bundle to produce normal physiological ventricular activation via the His-Purkinje system. However, the first report of permanent His bundle pacing, by Deshmukh et al., did not occur until 2000.2 In that study, His pacing was performed in a series of patients with… View more
Author(s): Demosthenes G Katritsis Added: 3 years ago
Mechanical dyssynchrony, ie nonsynchronous contraction of the wall segments of the left ventricle (intraventricular) or between the left and right ventricles (interventricular), impairs systolic function and ventricular filling, increases wall stress and worsens mitral regurgitation. It is most readily defined by the presence of QRS widening and left bundle branch block (LBBB) configuration on… View more