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High-Resolution Mapping in Patients with Persistent Atrial Fibrillation: A Case-based Review of the PENTARAY™ Catheter

… AF, but with persistent AF the success rate remains low at around 50-60%. 1 Success rates exceeding 70% are … to the development of ablation strategies to eliminate low-voltage regions caused by scarring within the LA. This … a high-density map from its 1 mm electrodes, covering an area of 6.25 cm 2 . 28 Compared with point-by-point voltage

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Atrial Fibrosis: Translational Considerations for the Management of AF Patients

… enhancement MRI or intraprocedurally using electroanatomic voltage mapping. The presence and extent of left atrial … between regions of scar identified by LGE-MRI and low-voltage areas identified by electroanatomic voltage … Muller et al. showed that a left atrial low-voltage area that was evaluated by intraprocedural mapping during AF …

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High-resolution Mapping in Patients with Persistent AF

… isolation (PVI). Scar tissue (as identified by contact voltage mapping) is found to be present in many of these … catheter ablation approach, targeting the patient-specific low voltage/fibrotic substrate can lead to improved outcomes. … Mapping systems create a 3D reconstruction of the area of interest and enable the location of catheters, maps …

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Contemporary Mapping Techniques of Complex Cardiac Arrhythmias – Identifying and Modifying the Arrhythmogenic Substrate

… Visualisation of catheters is confined into a 3D virtual area called the 'matrix', which can be built only by a … with eight splines. Each spline incorporates eight small, low impedance electrodes (64 electrodes in total). Electrode … acquired signal, which, in turn, influence the results of voltage-based substrate mapping. 14 Adequate contact between …

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A Decade of CFAE Mapping: Still Seeking More Specific Tools to Identify Sources and Substrate of Persistent Atrial Fibrillation

… CFEmean algorithm detects fractionated activity at high voltage (> 0.5 mV) - i.e. underdetecting CFAE within low voltage sites. 3 Similarly, another randomised clinical … versus continuous versus high voltage (> 0.5 mV) versus low voltage ( …

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Atrial Myopathy Underlying Atrial Fibrillation

… including ECG, plasma biomarkers, electroanatomical voltage mapping, echocardiography, and cardiac MRI, can help … when controlling for BMI. 30 Obese patients have increased low-voltage areas (13.9% versus 3.4%, p 0.06 mm/s was associated …

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Atrial Fibrillation Structural Substrates: Aetiology, Identification and Implications

… substrate , atrial remodelling , reverse remodelling , low-voltage area , electroanatomic mapping , Disclosure: RP is supported …

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Brugada Syndrome: Progress in Genetics, Risk Stratification and Management

… for rare gene variants other than SCN5A has been extremely low. 7 Furthermore, differentiation of rare pathogenic … shown that RVOT electroanatomical alterations (a low-voltage area) correlate with myocardial inflammation and arrhythmia …

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Drivers of Atrial Fibrillation: Theoretical Considerations and Practical Concerns

… appearance of AF. When they undertook local cooling of the area the arrhythmia terminated but restarted on … wave as the earliest activated site in the mapping area. The shortest time difference with the neighbouring …

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Epicardial Ventricular Tachycardia Ablation for Which Patients?

… first clue to an epicardial substrate is the absence of low-voltage areas or fractionated/abnormal electrograms during … endocardial bipolar voltage abnormality, however, the area of unipolar voltage abnormality (cut-off …

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