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Author(s):
Konstantinos D Rizas
,
Wolfgang Hamm
,
Stefan Kääb
,
et al
Added:
3 years ago
Experimental and clinical studies have demonstrated that enhanced sympathetic autonomic nervous system (SANS) activity can destabilise myocardial repolarisation,1–4 increasing vulnerability to developing fatal cardiac arrhythmias.5–8 Accordingly, assessment of SANS activity has always been a major goal for cardiac risk stratification methods. Various non-invasive methods including assessment of…
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Author(s):
Nikhil Singh
,
Kegan James Moneghetti
,
Jeffrey Wilcox Christle
,
et al
Added:
3 years ago
Considerable evidence supports the importance that the autonomic nervous system (ANS) has regarding cardiovascular health and prognosis.1 Specific variables derived from heart rate (HR) and heart rate variability (HRV) at rest and with exercise help assess the status of the ANS. Interest has also peaked on the use of HRV to assess the quality of an exercise programme. Among the athletic…
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Author(s):
Nikhil Singh
,
Kegan James Moneghetti
,
Jeffrey Wilcox Christle
,
et al
Added:
3 years ago
Estimation of Prognosis Using HRV
The association of heart rate variability (HRV) and prognosis, both for all-cause and cardiovascular (CV) mortality, has been studied using ECG at rest, with exercise and in the ambulatory setting. A meta-analysis by Hillebrand and colleagues found that, using both resting and ambulatory ECG monitoring, lower HRV is associated with a 32–45% increased risk of…
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Author(s):
Caroline H Roney
,
Andrew L Wit
,
Nicholas S Peters
Added:
3 years ago
Determining optimal treatment strategies for complex arrhythmogenesis in AF is confounded by the lack of consensus on the mechanisms causing AF. Fundamental to defining arrhythmogenic mechanisms of AF are the distinctions and interplay between functional features (determined by the electrophysiology of a cell) and structural features (determined by whether a structural or anatomical feature is…
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Impulse Dynamics
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Author(s):
Demosthenes G Katritsis
,
Bernard J Gersh
,
A John Camm
Added:
3 years ago
Early repolarisation pattern is defined electrocardiographically by a distinct J wave or J-point elevation that is either a notch or a slur of the terminal part of the QRS entirely above the baseline, with or without ST-segment elevation. The peak of the notch or slur (Jp) should be ≥0.1 mV in two or more contiguous leads, excluding leads V1 to V2 (see Figure 1).1,2 Early repolarisation syndromes…
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Author(s):
Manoj N Obeyesekere
,
Andrew D Krahn
Added:
3 years ago
Early repolarisation (ER) is defined as J-point elevation of ≥0.1 mV in two adjacent leads with either a slurred or notched morphology (Figures 1 to 4).1,2 Numerous studies have established an association with ER and increased risk of death and idiopathic ventricular fibrillation (VF).1–5 Clinicians face questions such as patient and family counselling, quantitifying the risk of sudden cardiac…
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Author(s):
Ilan Goldenberg
Added:
1 year ago
In this video from HRS 2022, Dr Ilan Goldenberg (University of Rochester Medical Center, Rochester, NY, US) joins us to discuss the findings of a recent study which aimed to evaluate the effect of sex hormones during the menstrual cycle on repolarisation dynamics in women with congenital and drug-induced long QT syndrome.
Discussion points:
1. Aim, and endpoints
2. Study design
3. Key findings
4…
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Author(s):
Jing Xian Quah
,
Dhani Dharmaprani
,
Anandaroop Lahiri
,
et al
Added:
2 years ago
Author(s):
Agnieszka Smoczynska
,
Henriëtte DM Beekman
,
Marc A Vos
Added:
3 years ago
The plasticity of the heart enables it to adapt to certain pathological insults and to maintain the cardiac output necessary to satisfy the metabolic requirements of the body.1 Although beneficial at first, this process of ventricular remodelling can have detrimental effects on cardiac function and contribute to arrhythmogenesis.2 Sudden cardiac death due to ventricular tachyarrhythmias accounts…
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