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Author(s): Abhishek Maan , Moussa Mansour , Jeremy N Ruskin , et al Added: 3 years ago
Atrial fibrillation (AF) is the most common cardiac arrhythmia encountered in clinical practice.1 It has been estimated that >3million people in the US and >4.5 million in the EU have paroxysmal or persistent AF.2–4 AF is associated with an approximately fivefold increased risk of stroke,5 threefold risk of heart failure,6 diminished quality of life7 and increased healthcare costs.8,9… View more

Electrophysiology & Arrhythmia
Machine Learning and Stroke Risk Prediction
Author(s): Yaacoub Chahine , Matthew J Magoon , Bahetihazi Maidu , et al Added: 1 year ago

Prevention & Chronic Conditions
Neuromodulation for Atrial Fibrillation
Author(s): Tolga Aksu , Jamario R Skeete , Henry H Huang Added: 1 year ago

Electrophysiology & Arrhythmia
Author(s): Antonio Sorgente , Riccardo Cappato Added: 3 years ago
Cardiac resynchronisation therapy (CRT) is a well-established non-pharmacological treatment option for patients with refractory symptomatic heart failure (HF) already under optimal medical therapy.1 CRT is founded on the principle that interventricular conduction disturbances and especially left bundle branch block (LBBB) are deleterious to cardiac performance and may contribute to the systolic… View more

Heart Failure

Electrophysiology & Arrhythmia
NOACs: Monitoring their Anticoagulant Effects and Use of Antidotes
Author(s): Nur A Rahmat , Gregory YH Lip Added: 3 years ago
Until recently, the vitamin K antagonist (VKA, e.g. warfarin) class of drugs was the only oral anticoagulant in use. VKAs have important inter- and intra-patient variability, influenced by diet, alcohol and drugs; thus, regular anticoagulation monitoring is necessary. Indeed, VKAs offer their best efficacy and safety when the average time in therapeutic range (TTR) is >65–70 % in a particular… View more

Electrophysiology & Arrhythmia
Author(s): Sebastian Clauss , Moritz F Sinner , Stefan Kääb , et al Added: 3 years ago
Atrial fibrillation (AF) is the most common arrhythmia experienced in clinical practice, and is responsible for significant morbidity and mortality.1 It affects more than 6 million people in Europe.1 The lifetime risk of developing AF after the age of 40 is approximately 25 %.1 AF is a major public health burden as it is associated with an increased risk of stroke by fivefold, dementia by twofold… View more

Electrophysiology & Arrhythmia

Prevention & Chronic Conditions
Author(s): Agnieszka Smoczynska , Henriëtte DM Beekman , Marc A Vos Added: 3 years ago
The plasticity of the heart enables it to adapt to certain pathological insults and to maintain the cardiac output necessary to satisfy the metabolic requirements of the body.1 Although beneficial at first, this process of ventricular remodelling can have detrimental effects on cardiac function and contribute to arrhythmogenesis.2 Sudden cardiac death due to ventricular tachyarrhythmias accounts… View more

Electrophysiology & Arrhythmia
Miracor Medical Systems
Miracor Medical Systems GmbH is an Austrian medical device company developing disruptive solutions to treat severe heart diseases; striving to bring back cardiac patients to normal life. Miracor develops and commercializes the PiCSO (Pressure-controlled Intermittent Coronary Sinus Occlusion) Impulse System,a technology platform designed toimprove clinical outcome of patients with impaired… View more
Job title: MD Washington University School of Medicine, St Louis, MO, US
Dr Mann is the Lewin Chair and Professor of Medicine, Cell Biology and Physiology, at the Washington University School of Medicine, and Cardiologist-in-chief at Barnes Jewish Hospital in St Louis, Missouri, US. His research focus has been the molecular and cellular basis of heart failure, with particular emphasis on the role of innate immunity in disease progression and recovery of the failing… View more
Assessment of Substrates, Genetics and Risk Factors
Author(s): Dominik Linz , Sander Verheule , Aaron Isaacs , et al Added: 2 years ago

Electrophysiology & Arrhythmia