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Author(s): Megan Barber , Jason Chinitz , Roy John Added: 3 years ago
Ventricular arrhythmias are designated idiopathic when demonstrable structural heart disease, significant coronary disease including coronary spasm or genetic arrhythmia syndromes are absent.1 These arrhythmias may be benign but are also a recognised cause of sudden cardiac death. The common form of idiopathic ventricular tachycardia (VT) originates in the ventricular outflow tracts, manifest… View more
Author(s): Alessio Galli , Francesco Ambrosini , Federico Lombardi Added: 3 years ago
Since the 1960s, Holter monitoring has been a cornerstone for diagnosing suspected arrhythmias in patients of all ages.1 The most common monitoring systems allow the continuous registration of three or more leads for 24–48 hours; newer Holter monitors allow continuous electrocardiogram (ECG) registration for 2 weeks.1 Extending the time of ECG registration will increase the diagnostic yield of… View more
Author(s): Brett Wanamaker , Thomas Cascino , Vallerie V McLaughlin , et al Added: 3 years ago
Pulmonary hypertension (PH) is a chronic condition that is characterised by elevated pulmonary vascular pressures and can be caused by several disease processes (see Table 1).1 Regardless of the aetiology, PH is a progressive disease with a clinical course characterised by frequent decompensations in advanced stages and often a poor prognosis despite the development of novel therapeutic agents.2… View more
Author(s): George D Katritsis , Hugh Calkins Added: 3 years ago
Over the past decades catheter ablation of atrial fibrillation (AF) has evolved from being a largely experimental procedure to a well-established therapeutic option for certain patients with AF.1–4 Currently the backbone of most catheter ablation techniques is to target the pulmonary veins (PVs) in order to achieve their electrical isolation and maintain sinus rhythm (SR).1 Additional techniques… View more
Author(s): Satoshi Higa , Li-Wei Lo , Shih-Ann Chen Added: 3 years ago
Catheter ablation of AF has become an established therapy and may have the potential to cure this most commonly encountered sustained arrhythmia. Previous studies have demonstrated that pulmonary veins (PVs) are a major source of the ectopic beats that initiate AF. PV isolation in patients with symptomatic paroxysmal AF refractory to antiarrhythmic drugs is effective; however, it is difficult to… View more
Author(s): Amir A Schricker , Junaid Zaman , Sanjiv M Narayan Added: 3 years ago
Catheter ablation is more effective than pharmacological therapy for the secondary prevention of patients with paroxysmal1,2 and persistent3,4 atrial fibrillation (AF) and has an emerging role in the primary prevention of paroxysmal AF.5,6 Nevertheless, in randomised clinical trials (RCTs) its success in treating patients with paroxysmal AF is 40–60% for a single procedure and 70% for multiple… View more