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Defining Left Bundle Branch Block Patterns in Cardiac Resynchronisation Therapy: A Return to His Bundle Recordings
Author(s): Roderick Tung , Gaurav A Upadhyay Added: 3 years ago
In 1970, Durrer et al. recorded the total excitation of the human heart with 870 electrodes and confirmed the first 10 ms of left ventricular (LV) activation as trifascicular in nature.1 The rapid and synchronous activation of the LV through the specialised His–Purkinje network is highly intricate and efficient, preserving normal physiological coupling between electrical excitation and mechanical… View more

Electrophysiology & Arrhythmia
Author(s): Ramanan Kumareswaran , Francis E Marchlinski Added: 3 years ago
Ventricular tachycardia (VT) is one of the most challenging medical conditions faced by cardiac patients and physicians treating them. Antiarrhythmic medications have limited effectiveness and are frequently poorly tolerated.1–4 Catheter ablation is increasingly used to treat patients successfully.1,5–7 Most VTs can be ablated endocardially but some require epicardial mapping and ablation… View more

Electrophysiology & Arrhythmia
Author(s): George Thomas , Jiwon Kim , Bruce B Lerman Added: 3 years ago
CRT is an essential treatment for patients with heart failure and reduced ejection fraction as it can restore left ventricular (LV) electrical and mechanical synchrony. It has been shown to increase quality of life, improve functional status, reduce hospitalisation, improve LV systolic function and reduce mortality in properly selected patients.1,2 While CRT is an effective therapy, approximately… View more

Heart Failure

Electrophysiology & Arrhythmia
Physiology and Practicality of Left Ventricular Septal Pacing
Author(s): Luuk Heckman , Justin Luermans , Floor Salden , et al Added: 2 years ago

Electrophysiology & Arrhythmia
Electrical Mapping to Optimise Heart Failure Outcomes Following Cardiac Resynchronisation Therapy
Author(s): David O’Donnell Added: 8 years ago

Heart Failure

Electrophysiology & Arrhythmia
Author(s): Mario Njeim , Frank Bogun Added: 3 years ago
Percutaneous ablation for ventricular tachycardia (VT) was first attempted in 1983 and has rapidly evolved to become an important option for controlling recurrent VTs.1 Endocardial ablation remained the only percutaneous approach until epicardial access was introduced by Sosa et al. in 1996 and thereafter became progressively more available as an adjunctive strategy for the treatment of… View more

Imaging & Diagnostics

Heart Failure
Impact of Micro-, Mini- and Multi-Electrode Mapping on Ventricular Substrate Characterisation
Author(s): Benjamin Berte , Katja Zeppenfeld , Roderick Tung Added: 3 years ago
Accurate substrate characterisation is important for depicting scar-related re-entrant tachycardia to optimise ablation targets and strategies. The underlying substrate can be analysed using electrogram (EGM) characteristics, such as low voltage, local abnormal voltage activity (LAVA), evoked potentials or late potentials, conduction analysis in sinus rhythm or differential pacing, or using… View more

Electrophysiology & Arrhythmia
Value of Sinus Rhythm Mapping
Author(s): Mathijs S van Schie , Natasja MS de Groot Added: 1 year ago

Electrophysiology & Arrhythmia
Author(s): Geoffrey F Lewis , Michael R Gold Added: 3 years ago
Since the introduction of CRT more than 20 years ago, its role in mild to severe systolic heart failure has become well established. CRT has been shown to decrease mortality, reduce heart failure hospitalisations and improve functional status in patients with NYHA class II–IV heart failure and QRS prolongation, most commonly with LBBB pattern.1 One of the major limitations of CRT implementation… View more

Heart Failure

Electrophysiology & Arrhythmia
Septal and Conduction System Pacing
Author(s): Demosthenes G Katritsis , Hugh Calkins Added: 6 months ago

Electrophysiology & Arrhythmia