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Author(s):
Antonio Zaza
,
Carlotta Ronchi
,
Gabriella Malfatto
Added:
3 years ago
The incidence of ventricular arrhythmias is often related, within an individual, to the rate of their underlying sinus rhythm (heart rate). The direction of this relationship is generally considered to entail some prognostic significance: whereas ectopic activity suppressed by tachycardia is assumed to be benign, an arrhythmia enhanced by tachycardia is regarded with more concern. Is this…
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Author(s):
David J Sprenkeler
,
Marc A Vos
Added:
3 years ago
The concept of post-extrasystolic potentiation (PESP), which describes the phenomenon of increased contractility of the beat following an extrasystole, has intrigued physiologists and clinicians for more than 120 years. Since its first description in 1885 by Oskar Langendorff,1 PESP has become a widely debated concept, not only for its fundamental basis but also because of the potential…
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Author(s):
Alexander Steger
,
Daniel Sinnecker
,
Petra Barthel
,
et al
Added:
3 years ago
In 1885, Oscar Langendorff was the first person to describe the increase in contractility (‘Pulsverstärkung‘) that follows an extrasystole.1Langendorff experimented with spontaneously beating isolated frog hearts. He recorded the heartbeats by using a lever that transferred the contractile movements of the heart to a rotating drum. Electrical stimulation resulted in premature contractions that…
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Author(s):
Marwan M Refaat
,
Jad Ballout
,
Moussa Mansour
Added:
3 years ago
Although there is no formal database of adults with congenital heart disease (CHD) in the United States, the prevalence and incidence of CHD can be estimated and extrapolated from data in the Canadian providence.1 As such, the prevalence of CHD in the United States has been estimated in 2010 to be around 2.4 million people (1.4 million adults and 1 million children), with an incidence of between…
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Author(s):
Krystien VV Lieve
,
Arthur A Wilde
,
Christian van der Werf
Added:
3 years ago
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare but severe genetic cardiac arrhythmia disorder. Clinically, CPVT most often presents in childhood with symptoms such as syncope or sudden cardiac death due to polymorphic ventricular tachycardia (VT) or ventricular fibrillation typically triggered by exercise or emotions in the absence of structural heart disease.1
Mutations…
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Author(s):
Abhishek Bhaskaran
,
John Fitzgerald
,
Nicholas Jackson
,
et al
Added:
3 years ago
Author(s):
Nikolaos Papageorgiou
,
Neil T Srinivasan
Added:
2 years ago
Author(s):
Brenton S Bauer
,
Anthony C Li
,
Jason S Bradfield
Added:
3 years ago
Ventricular arrhythmias (VA) are commonly associated with structural heart disease and have substantial impact on patient outcomes and health system costs. Within the realm of cardiomyopathy (CM), there has been substantial progress with respect to ischaemic CM (ICM) in the understanding of infarct related scar biology and scar-mediated ventricular tachycardia (VT).
This has led to interventions…
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Author(s):
Satish Raj
,
Robert Sheldon
Added:
3 years ago
Syncope and palpitations are two common clinical presentations, and both pose difficulties in the approach to their management. They are both symptoms of a number of syndromes, and an efficient approach with targeted therapy is challenging. Cardiac arrhythmia specialists, who lack a compact and accessible guide to management, see many patients with these symptoms in consultation. Recognising this…
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Author(s):
Manyoo A Agarwal
,
Aadhavi Sridharan
,
Rhea C Pimentel
,
et al
Added:
10 months ago