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Author(s): Luca Sala , Massimiliano Gnecchi , Peter J Schwartz Added: 3 years ago
Long QT Syndrome Long QT syndrome (LQTS) is a potentially severe arrhythmogenic disorder, affecting more than one in 2,000 people worldwide.1 It is characterised by a marked prolongation of the QT interval on the electrocardiogram and major cardiac events, such as syncope, cardiac arrest or sudden death, especially under conditions of physical or emotional stress.2,3 The current diagnostic… View more

Electrophysiology & Arrhythmia
Joseph C. Wu
Research Area(s) / Expertise:

Imaging

Cardio-oncology

Congenital Heart Disease

 Job title: Director
A cardiologist with board certification, Dr. Wu. is the Simon H. Stertzer, MD, Professor of Medicine and Radiology at Stanford University School of Medicine and the director of the Stanford Cardiovascular Institute. Dr. Wu was also chosen by the American Heart Association to serve as its president-elect for the 2022–2023 fiscal year. He conducts extensive research focussing on clinical… View more
Marco Valgimigli
Research Area(s) / Expertise: Job title: Deputy Chief of Cardiology
Prof Marco Valgimigli is an Interventional Cardiologist and Deputy Chief of Cardiology at the Cardiocentro Ticino Institute in Lugano, Switzerland.He obtained his medical degree from the University of Bologna, and completed his training in internal medicine at the same university. He received a degree in cardiological sciences at the University of Ferrara and a PhD in interventional cardiology at… View more
Author(s): Andrew Grace Added: 3 years ago
Our society acquires and stores data at unprecedented rates. Making sense of it has become a subject of academic interest,1,2 it is widely discussed and has provided a focus of interest to professional advisors,3 in each case with the objective of considering practical applications. Sophisticated interpretation of these data can provide powerful insights. Just recently, in the field of public… View more

Digital Health
Author(s): Dario DiFrancesco Added: 3 years ago
HCN4 (hyperpolarisation-activated, cyclic nucleotide gated 4) channels, the pore-forming α–subunits of ‘funny’ channels originally described in pacemaker cells of the sinoatrial node (SAN),1 are responsible for the early phase of diastolic depolarisation in these cells and are key determinants of pacemaker generation and control of heart rate.2–5 HCN4 channels are selectively expressed in the SAN… View more

Electrophysiology & Arrhythmia
Relationship Between Obstructive Sleep Apnoea and AF
Author(s): Ghanshyam Shantha , Frank Pelosi , Fred Morady Added: 3 years ago
Prevalence of AF and Obstructive Sleep Apnoea Nonvalvular AF is the most common sustained arrhythmia, affecting nearly 3 million adult Americans.1–4 By 2050, nearly 12–15 million adults in the US will have AF.1 The global prevalence of obstructive sleep apnoea (OSA) is also increasing. OSA is the most common form of sleep-disordered breathing, affecting 10–15% of the general population (6–9% in… View more

Electrophysiology & Arrhythmia

Prevention & Chronic Conditions
Author(s): Philippe Charron , Eloisa Arbustini , Gisèle Bonne Added: 3 years ago
Most mutations of the LMNA gene affect the heart, causing a dilated cardiomyopathy, ususally with conduction defect and ventricular arrhythmia, with or without skeletal muscle involvement. Although a relatively rare disease, cardiologists should be aware of laminopathies (diseases caused by LMNA gene mutations) because of the particularly aggressive course compared with most other… View more

Heterogeneous Populations

Electrophysiology & Arrhythmia
Ventricular Arrhythmia after Acute MI
Author(s): Justine Bhar-Amato , William Davies , Sharad Agarwal Added: 3 years ago
Ventricular tachyarrhythmias (VAs) most commonly occur early in ischaemia, and patients presenting with an acute MI and ventricular arrhythmias are a group that has a significantly increased risk of mortality.1,2 Thrombolysis primary percutaneous coronary intervention (PCI) and use of beta-blockers, while resulting in the modification of the natural history of an infarct, have also reduced the… View more

Electrophysiology & Arrhythmia

MI/ACS
Arrhythmias and Conduction Disturbances in Autoimmune Rheumatic Disorders
Author(s): Sotiris C Plastiras , Haralampos M Moutsopoulos Added: 3 years ago

Electrophysiology & Arrhythmia
At the Atrioventricular Crossroads: Dual Pathway Electrophysiology
Author(s): Sharon A George , N Rokhaya Faye , Alejandro Murillo-Berlioz , et al Added: 3 years ago
More than 100years have passed since the atrioventricular node (AVN) was first discovered by Sunao Tawara1 and described as a “Knoten” of tissue located at the proximal end of the Bundle of His (BoH).2 Despite the numerous advances in knowledge regarding the structure and function of the AVN, there are still several controversies that need to be addressed in both clinical and scientific settings… View more

Electrophysiology & Arrhythmia