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Author(s):
Saagar Mahida
,
Frédéric Sacher
,
Nicolas Derval
,
et al
Added:
3 years ago
Atrial fibrillation (AF) is the most commonly encountered arrhythmia in clinical practice. The discovery that pulmonary veins (PV) play a prominent role in the pathogenesis of AF has revolutionised the management of AF. PV isolation has become the most widely used technique for treatment of paroxysmal AF. Since the initial discovery implicating PVs in AF pathogenesis, the mechanistic link between…
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Author(s):
Penelope A Boyden
,
Wen Dun
,
Bruno D Stuyvers
Added:
3 years ago
Abnormalities in electrical rhythm were studied by Einthoven at the start of the 20th century. In the 1940s, studies by Bozler et al.1 described contractile signals that appeared to be ‘triggered’ heart beats. Today we use the term delayed afterdepolarisations (DADs) to refer to oscillations in voltage that follow a driven action potential.
In the mid-1970s, progress was made when Lederer and…
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Author(s):
Jean-Baptiste Gourraud
,
Jason G Andrade
,
Laurent Macle
,
et al
Added:
3 years ago
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia observed in clinical practice, occurring in approximately 2 % of the general population.1–3 A progressive increase in both the prevalence and incidence of AF has been demonstrated in recent years, defining AF as a major economic and public health issue.1
The identification of sites of AF initiation and/or maintenance within…
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Author(s):
Megan Barber
,
Jason Chinitz
,
Roy John
Added:
3 years ago
Ventricular arrhythmias are designated idiopathic when demonstrable structural heart disease, significant coronary disease including coronary spasm or genetic arrhythmia syndromes are absent.1 These arrhythmias may be benign but are also a recognised cause of sudden cardiac death. The common form of idiopathic ventricular tachycardia (VT) originates in the ventricular outflow tracts, manifest…
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Added:
6 years ago
Author(s):
Krystien VV Lieve
,
Arthur A Wilde
,
Christian van der Werf
Added:
3 years ago
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare but severe genetic cardiac arrhythmia disorder. Clinically, CPVT most often presents in childhood with symptoms such as syncope or sudden cardiac death due to polymorphic ventricular tachycardia (VT) or ventricular fibrillation typically triggered by exercise or emotions in the absence of structural heart disease.1
Mutations…
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Author(s):
Caroline H Roney
,
Andrew L Wit
,
Nicholas S Peters
Added:
3 years ago
Determining optimal treatment strategies for complex arrhythmogenesis in AF is confounded by the lack of consensus on the mechanisms causing AF. Fundamental to defining arrhythmogenic mechanisms of AF are the distinctions and interplay between functional features (determined by the electrophysiology of a cell) and structural features (determined by whether a structural or anatomical feature is…
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Author(s):
Dhanunjaya Lakkireddy
Added:
2 months ago
AFSymposium 2024 — In this interview, investigator, Dr Dhanunjaya Lakkireddy (Kansas City Heart Rhythm Institute, US) shares the key findings from the aMAZE Continued Access Protocol (AtriCure).This study is the extension of the aMAZE Trial investigation in the form of a nested, non-randomised registry. The study looked at the LARIAT System, which percutaneously isolates and ligates the left…
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Unmasking Adenosine
Author(s):
Gareth DK Matthews
,
Andrew Grace
Added:
3 years ago
Article
Author(s):
Domenico G Della Rocca
,
Sanghamitra Mohanty
,
Chintan Trivedi
,
et al
Added:
3 years ago
AF is the most common sustained arrhythmia, and carries an increased risk of cardiovascular and cerebrovascular complications. The latest estimates on the prevalence of AF portray an alarming scenario, with a steep increase in the number of people developing AF and prediction that the number affected will more than double in the next 40 years.1 Among the strategies to restore and maintain sinus…
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