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Author(s):
Maria Min-Young Kim
Added:
2 years ago
In this interview, Dr Maria Min-Young Kim (Imperial College Healthcare NHS Trust, London, UK) discusses the results of the GANGLIA-AF Trial, a study that aimed to determine the role of ectopy-triggering ganglionated plexus ablation (ET-GP) in the treatment of Atrial Fibrillation.
Questions:
1. Please summarise the main aims, study design and endpoints of this trial?
2. What were your key…
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Author(s):
Amir S Jadidi
,
Thomas Arentz
Added:
3 years ago
Adecade after its first description as ‘the electrophysiological substrate’ of atrial fibrillation,1 mapping complex fractionated atrial electrogram (CFAE) as an ablation target for atrial fibrillation (AF) remains highly controversial. Early high-density mapping studies of induced AF in humans revealed distinct mechanisms that underlie electrogram fractionation: collision areas of distinct…
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Author(s):
Konstantinos D Rizas
,
Wolfgang Hamm
,
Stefan Kääb
,
et al
Added:
3 years ago
Experimental and clinical studies have demonstrated that enhanced sympathetic autonomic nervous system (SANS) activity can destabilise myocardial repolarisation,1–4 increasing vulnerability to developing fatal cardiac arrhythmias.5–8 Accordingly, assessment of SANS activity has always been a major goal for cardiac risk stratification methods. Various non-invasive methods including assessment of…
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Author(s):
Nikhil Singh
,
Kegan James Moneghetti
,
Jeffrey Wilcox Christle
,
et al
Added:
3 years ago
Considerable evidence supports the importance that the autonomic nervous system (ANS) has regarding cardiovascular health and prognosis.1 Specific variables derived from heart rate (HR) and heart rate variability (HRV) at rest and with exercise help assess the status of the ANS. Interest has also peaked on the use of HRV to assess the quality of an exercise programme. Among the athletic…
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Author(s):
Saad Fyyaz
,
Michael Papadakis
Added:
1 year ago
Author(s):
Nur A Rahmat
,
Gregory YH Lip
Added:
3 years ago
Until recently, the vitamin K antagonist (VKA, e.g. warfarin) class of drugs was the only oral anticoagulant in use. VKAs have important inter- and intra-patient variability, influenced by diet, alcohol and drugs; thus, regular anticoagulation monitoring is necessary. Indeed, VKAs offer their best efficacy and safety when the average time in therapeutic range (TTR) is >65–70 % in a particular…
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Ignacio J Amat-Santos
Job title: Director, Cardiac Catheterization & Interventional Cardiology
Author
Mats Borjesson
Job title: Professor/ Chief physician
Author
Fernando Gallardo
Job title: Consultant Angiology and Vascular Surgeon
Author
Jonathan S Steinberg
Research Area(s) / Expertise:
Job title: Professor
Author