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Nesan Shanmugam
Research Area(s) / Expertise: Job title: Consultant Cardiologist and Honorary Senior Lecturer
Dr Shanmugam graduated from King’s College, University of London with a BSc (Hons) in 1998. He trained on the South West London Cardiology rotation and completed specialist cardiology training in 2013. He completed an international fellowship at the National Heart Centre/Duke-NUS Singapore in device therapy and advanced cardiac imaging, before being appointed as a consultant cardiologist in… View more
Management of Cardiac Sarcoidosis in 2020
Author(s): Nisha Gilotra , David Okada , Apurva Sharma , et al Added: 3 years ago
Sarcoidosis is an inflammatory granulomatous disease that can affect any organ. Systemic sarcoidosis is known to affect young adults, with a second peak in women >50 years of age, as demonstrated in Scandinavian and Japanese studies.1–4 In the US, the lifetime risk of sarcoidosis is 2.4% for black people and 0.85% for white people.1 The incidence of cardiac involvement has been increasingly… View more

Electrophysiology & Arrhythmia
Author(s): Deniz Akdis , Corinna Brunckhorst , Firat Duru , et al Added: 3 years ago
Arrhythmogenic cardiomyopathy (ACM) is usually referred to as arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D).1A first historical description was made in 1736, whereas its first modern description dates back to 1982.2 Initially, ACM was thought to be an embryological malformation.3 Yet in recent years it became evident that the pathophysiology of an ongoing genetically… View more

Heart Failure
Multimodality Imaging to Guide Ventricular Tachycardia Ablation in Patients with Non-ischaemic Cardiomyopathy
Author(s): Ling Kuo , Jackson J Liang , Saman Nazarian , et al Added: 3 years ago
Catheter ablation has been increasingly used as a treatment for refractory ventricular tachycardia (VT) in patients with non-ischaemic cardiomyopathy (NICM). However, ablation outcomes tend to be quite variable because of the heterogeneity of the aetiology for the NICM and associated VT substrate in these patients.1–3 Patients with NICM can be sub-classified based on specific genotypic and… View more

Imaging & Diagnostics

Electrophysiology & Arrhythmia
Catheter Ablation in Patients with Heart Failure and AF
Author(s): Sandeep Prabhu , Wei H Lim Added: 3 years ago
Heart failure (HF) and AF are two conditions that are increasing in prevalence worldwide.1,2 They frequently co-exist and in recent years, the clinical and physiological intersection between arrhythmia and HF has become an area of renewed interest, particularly as interventional treatments for rhythm disorders have advanced and moved into the mainstream of cardiac management. In particular, AF,… View more

Heart Failure

Electrophysiology & Arrhythmia
Author(s): Sebastiaan RD Piers , Katja Zeppenfeld Added: 3 years ago
Over the last 20 years ventricular tachycardia (VT) ablation has evolved from a treatment modality for selected patients withrecurrent haemodynamically tolerated VT (which can be mapped during ongoing arrhythmia), to a therapeutic option for patients with tolerated and untolerated VT using substrate-based ablation strategies.1 The substrate for VT after myocardial infarction (MI) consists of… View more

Imaging & Diagnostics

Electrophysiology & Arrhythmia
Author(s): Brenton S Bauer , Anthony C Li , Jason S Bradfield Added: 3 years ago
Ventricular arrhythmias (VA) are commonly associated with structural heart disease and have substantial impact on patient outcomes and health system costs. Within the realm of cardiomyopathy (CM), there has been substantial progress with respect to ischaemic CM (ICM) in the understanding of infarct related scar biology and scar-mediated ventricular tachycardia (VT). This has led to interventions… View more

Heart Failure
Author(s): Laurent Roten , Matthew Daly , Patrizio Pascale , et al Added: 3 years ago
With an ageing population and widespread use of implantable cardioverter-defibrillators, physicians are confronted with an increasing number of patients with symptomatic, drug-refractory ventricular tachycardia (VT). Catheter ablation is an important treatment option in the management of patients with structural heart disease and VT.1,2 In many patients, VT can be successfully ablated from the… View more

Electrophysiology & Arrhythmia