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3 years ago
Ventricular arrhythmias (VA) are commonly associated with structural heart disease and have substantial impact on patient outcomes and health system costs. Within the realm of cardiomyopathy (CM), there has been substantial progress with respect to ischaemic CM (ICM) in the understanding of infarct related scar biology and scar-mediated ventricular tachycardia (VT).
This has led to interventions…
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3 years ago
Sarcoidosis is an inflammatory granulomatous disease that can affect any organ. Systemic sarcoidosis is known to affect young adults, with a second peak in women >50 years of age, as demonstrated in Scandinavian and Japanese studies.1–4 In the US, the lifetime risk of sarcoidosis is 2.4% for black people and 0.85% for white people.1 The incidence of cardiac involvement has been increasingly…
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3 years ago
The use of cardiovascular implantable electronic devices (CIEDs) has increased dramatically, with approximately 1.2–1.4 million CIEDs implanted annually worldwide.1 In the US alone, there are more patients with CIEDs than registered nurses.2,3 CIEDs use leads that connect a generator to cardiac tissue to treat patients with many conditions including symptomatic bradycardia, morbid tachycardia…
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3 years ago
Cardiac implantable electronic device (CIED) therapy is effective and safe. However, infections related to CIED treatment may have devastating consequences, causing significant morbidity, mortality and generating considerable healthcare costs.1–6 Temporal trends in CIED treatment indicate a disproportional increase in CIED infections relative to implantation rates.1,7,8 Reasons for this trend are…
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2 years ago
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3 years ago
Cardiac resynchronisation therapy (CRT) is a widely-performed standard treatment for improving cardiac function and quality of life in patients with heart failure.1 After CRT, however, 30–40 % of patients do not experience improvements in left ventricular (LV) function and clinical symptoms.2–3 The key factors for increasing the response rate to CRT are identification of the optimal LV lead…
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3 years ago
The increasing use of cardiac implantable electronic devices (CIEDs) for management of cardiac conditions has over the last few years been associated with higher infection rates.1 Expanded CIED use alone cannot account for this rise,2–4 which involves both patient- and device-related factors. Indeed patients are tending to be older and presenting with co-morbidities, while devices are becoming…
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3 years ago
Maintenance of sinus rhythm in patients with non-paroxysmal AF is often challenging and complex. Catheter ablation is usually superior to anti-arrhythmic drug therapy alone. However, recurrence rates are high and have remained suboptimal. Although pulmonary vein isolation (PVI) is usually effective in treating paroxysmal AF, it is not sufficient for many patients with non-paroxysmal AF,…
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3 years ago
Over the last few decades an increasing body of evidence has supported the role of cardiovascular implantable electronic devices (CIEDs) including permanent pacemakers (PPMs), implantable cardioverter-defibrillators (ICDs) and cardiac resynchronisation therapy (CRT-D [with defibrillator] and CRT-P [without defibrillator]) in improving quality of life and survival.1 In addition, there has been a…
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Added:
4 months ago
